Protein Alignment l(2)efl and Cryaa

DIOPT Version :10

• Sequence 1: NP_523827.1
• Gene: l(2)efl / 37744
• FlyBaseID: FBgn0011296
• Length: 187
• Species: Drosophila melanogaster
• Sequence 2: NP_001265498.1
• Gene: Cryaa / 12954
• MGIID: 88515
• Length: 202
• Species: Mus musculus
• Alignment Length: 203
• Identity: 71/203 - (34%)
• Similarity: 102/203 - (50%)
• Gaps: 37/203 - (18%)

  Fly    11 WWDELDFPMRTSRLLDQHFGQGLKRDDLM------------SSVWNSRPTVLRSG----YLRPWH 59
            |:.....|...|||.||.||:||...||:            .|::.   |||.||    ....|.
Mouse     9 WFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFR---TVLDSGISELMTHMWF 70

  Fly    60 T----------NSLQKQESGSTLNIDSEKFEVILDVQQFSPSEITVKVADKFVIVEGKHEEKQDE 114
            .          |:..|....:.:..|.:||.:.|||:.|||.::||||.:.||.:.|||.|:||:
Mouse    71 VMHQPHAGNPKNNPVKASYMAKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDD 135

  Fly   115 HGYVSRQFSRRYQLPSDVNPDTVTSSLSSDGLLTIKAP--MKALPPPQTERLVQITQTGPSSKED 177
            |||:||:|.|||:|||:|:...::.|||:||:||...|  ...|....:||.:      |.|:|:
Mouse   136 HGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSERAI------PVSREE 194

  Fly   178 NAKKVETS 185
            ......:|
Mouse   195 KPSSAPSS 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_523827.1	metazoan_ACD	71..153	CDD:107247	42/83 (51%)
Cryaa	NP_001265498.1	Crystallin	1..54	CDD:425732	14/44 (32%)
		alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.	90..174	CDD:469641	41/83 (49%)