Protein Alignment l(2)efl and HSPB6

DIOPT Version :9

• Sequence 1: NP_001261156.1
• Gene: l(2)efl / 37744
• FlyBaseID: FBgn0011296
• Length: 187
• Species: Drosophila melanogaster
• Sequence 2: NP_653218.1
• Gene: HSPB6 / 126393
• HGNCID: 26511
• Length: 160
• Species: Homo sapiens
• Alignment Length: 152
• Identity: 62/152 - (40%)
• Similarity: 80/152 - (52%)
• Gaps: 38/152 - (25%)

  Fly    23 RLLDQHFGQGLKRDDLMSSVWNSRPTVLRSGYLR--------------PWHTNSLQKQESGSTLN 73
            ||.||.||:||...:|.:..    ||.|...|||              |.|
Human    27 RLFDQRFGEGLLEAELAALC----PTTLAPYYLRAPSVALPVAQVPTDPGH-------------- 73

  Fly    74 IDSEKFEVILDVQQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSDVNPDTVT 138
                 |.|:|||:.|||.||.|||..:.|.|..:|||:.||||:|:|:|.|||:||..|:|..||
Human    74 -----FSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVT 133

  Fly   139 SSLSSDGLLTIK-APMKALPPP 159
            |:||.:|:|:|: ||..|..||
Human   134 SALSPEGVLSIQAAPASAQAPP 155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_001261156.1	metazoan_ACD	71..153	CDD:107247	41/82 (50%)
HSPB6	NP_653218.1	Involved in stabilization of the HSPB1:HSBP6 heterodimer. /evidence=ECO:0000269|PubMed:27717639	1..72		15/48 (31%)
		Crystallin	3..58	CDD:395419	15/34 (44%)
		ACD_HspB4-5-6	66..144	CDD:107233	41/96 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4724
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	1	1.000	-	-		otm41738
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45640
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X393
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	8.070