DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(2)efl and Hspb8

DIOPT Version :9

Sequence 1:	NP_001261156.1	Gene:	l(2)efl / 37744	FlyBaseID:	FBgn0011296	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_446064.1	Gene:	Hspb8 / 113906	RGDID:	71003	Length:	196	Species:	Rattus norvegicus

Alignment Length:	157	Identity:	63/157 - (40%)
Similarity:	87/157 - (55%)	Gaps:	20/157 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DFPMRTSRLLDQHFGQGLKRDDL-----------MSSVWNSRPTVLRSGYLRPWHTNSLQ---KQ 66
            |.|: :|||||..||.....|||           :||.|   |..||||.:....|.:.:   ..
  Rat    23 DSPL-SSRLLDDGFGMDPFPDDLTAPWPEWALPRLSSAW---PGTLRSGMVPRGPTATARFGVPA 83

  Fly    67 ESGSTLNIDSEKFEVILDVQQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSD 131
            |..:......|.::|.::|..|.|.|:.||..|.:|.|.|||||||.|.|.||:.|:::.|||::
  Rat    84 EGRNPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAE 148

  Fly   132 VNPDTVTSSLSSDGLLTIKAPMKALPP 158
            |:|.||.:|||.:|||.|:||.  :||
  Rat   149 VDPVTVFASLSPEGLLIIEAPQ--VPP 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_001261156.1	metazoan_ACD	71..153	CDD:107247	38/81 (47%)
Hspb8	NP_446064.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		2/5 (40%)
		ACD_HspB8_like	80..170	CDD:107235	39/89 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..196
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342807
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750