DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment St1 and Sult1b1

DIOPT Version :9

Sequence 1:	NP_611815.3	Gene:	St1 / 37742	FlyBaseID:	FBgn0034887	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_071958.1	Gene:	Sult1b1 / 64305	RGDID:	708534	Length:	299	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	90/297 - (30%)
Similarity:	147/297 - (49%)	Gaps:	33/297 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWM 83
            |.|..||..::|.:.       .||               ::.:|:.|..|:.|.|.||.||||:
  Rat    12 LKIIHGYPMVYAFAL-------GWE---------------KIEEFQSRPCDIVIPTYPKSGTTWL 54

  Fly    84 QELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPR 148
            .|:..:|:|:.:....|...:|.:.|.||.|  ||......:......||||:||:|||..:||:
  Rat    55 SEIVDMVLNDGNVGKCKRDVITSKVPMLEQN--VPGARRSGVELLKKTPSPRIIKTHLPIDLLPK 117

  Fly   149 QIWSKRPKIIYVYRNPKDAAISYFHH--WRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQ 211
            ..|..:.|:||:.||.||.|:||:|.  ...:....||..:::..|:.|.|.:...:.|:..:|:
  Rat   118 SFWDNKCKMIYLARNGKDVAVSYYHFDLMNNIQPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWE 182

  Fly   212 LRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVK-EFE 275
            .|....|.|..||.:|....:.|.::|.||::::.:..::::..|.|||.|:|||..|:.. ..|
  Rat   183 KREGHPILFLYYEDLKKNPKKEIKKIANFLDKTLDEHTLERIVHHTSFEVMKDNPLVNYTHLPTE 247

  Fly   276 SMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFD 312
            .|      :..:..|:|:||||..|:..|.....:||
  Rat   248 IM------DHSKSPFMRKGVVGDWKNYFTMTQSEKFD 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St1	NP_611815.3	Sulfotransfer_1	67..322	CDD:279075	81/249 (33%)
Sult1b1	NP_071958.1	Sulfotransfer_1	40..289	CDD:279075	81/247 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351350
Domainoid	1	1.000	153	1.000	Domainoid score	I4182
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H69169
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4144
OMA	1	1.010	-	-		QHG49491
OrthoDB	1	1.010	-	-		D481448at33208
OrthoFinder	1	1.000	-	-		FOG0000045
OrthoInspector	1	1.000	-	-		mtm12324
orthoMCL	1	0.900	-	-		OOG6_100094
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.710