DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment St1 and Sult1b1

DIOPT Version :9

Sequence 1:	NP_611815.3	Gene:	St1 / 37742	FlyBaseID:	FBgn0034887	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001343872.1	Gene:	Sult1b1 / 56362	MGIID:	2136282	Length:	299	Species:	Mus musculus

Alignment Length:	291	Identity:	87/291 - (29%)
Similarity:	148/291 - (50%)	Gaps:	31/291 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAW 88
            ||..|:|.:.       |||               |:.:|:....|:.|.|.||.||||:.|:..
Mouse    17 GYPMIYAFAL-------NWE---------------RIEEFQSTPGDIVITTYPKSGTTWLSEIVD 59

  Fly    89 LVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSK 153
            :|:|:.:.|..|...:|.:.|.||.:  ||.:....:......||||:||:|||..:||:..|..
Mouse    60 MVLNDGNVEKCKRDVITSKVPMLELS--VPGIRISGVELLKKTPSPRIIKTHLPIDLLPKSFWEN 122

  Fly   154 RPKIIYVYRNPKDAAISYFHH--WRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEP 216
            :.|:||:.||.||.|:||:|.  ...:....||..:::..|:.|.|.:...:.|:..:|:.|.|.
Mouse   123 KCKMIYLARNGKDVAVSYYHFDLMNSINPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREEH 187

  Fly   217 NIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAA 281
            .:.:..||.:|....:.|.::|.||::::.:|.:.::..|.|||.|::||..|:     :....|
Mouse   188 PLLYLYYEELKQNPKKEIKKIASFLDKTLDEEALDRIVHHTSFEMMKENPLVNY-----THLPTA 247

  Fly   282 GREVEEFRFVRRGVVGSHKDELTADIIREFD 312
            ..:..:..|:|:|:||..|:..|.....:||
Mouse   248 MMDHSKSPFMRKGIVGDWKNYFTMTQTEQFD 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St1	NP_611815.3	Sulfotransfer_1	67..322	CDD:279075	78/248 (31%)
Sult1b1	NP_001343872.1	Sulfotransfer_1	38..289	CDD:395556	78/248 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847786
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H69169
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4116
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49491
OrthoDB	1	1.010	-	-		D481448at33208
OrthoFinder	1	1.000	-	-		FOG0000045
OrthoInspector	1	1.000	-	-		otm44260
orthoMCL	1	0.900	-	-		OOG6_100094
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.710