DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment St1 and SULT1B1

DIOPT Version :9

Sequence 1:	NP_611815.3	Gene:	St1 / 37742	FlyBaseID:	FBgn0034887	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	XP_005265733.1	Gene:	SULT1B1 / 27284	HGNCID:	17845	Length:	301	Species:	Homo sapiens

Alignment Length:	302	Identity:	90/302 - (29%)
Similarity:	147/302 - (48%)	Gaps:	43/302 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LAISGGY--SSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTT 81
            |.:..||  :..|||         |||               ::..|..|.||:.|.|.||.|||
Human    17 LKLVHGYPMTCAFAS---------NWE---------------KIEQFHSRPDDIVIATYPKSGTT 57

  Fly    82 WMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWML 146
            |:.|:..:::|:.|.|..|...:|.:.|.||.  .:|.:....|......||||::|:|||..:|
Human    58 WVSEIIDMILNDGDIEKCKRGFITEKVPMLEM--TLPGLRTSGIEQLEKNPSPRIVKTHLPTDLL 120

  Fly   147 PRQIWSKRPKIIYVYRNPKDAAISYFHH--WRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDF 209
            |:..|....|:||:.||.||.::||:|.  ...:..:.||..:::..|:.|.|.:...:.|:.::
Human   121 PKSFWENNCKMIYLARNAKDVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNW 185

  Fly   210 WQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNH---- 270
            |:.:.|..|.|..||.||....:.|.::.:|||::::.|.:.::..|.|||.|:|||..|:
Human   186 WKKKEEHPILFLYYEDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLP 250

  Fly   271 VKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFD 312
            ....:..|:.         |:|:|..|..|:..|.....:||
Human   251 TTVMDHSKSP---------FMRKGTAGDWKNYFTVAQNEKFD 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St1	NP_611815.3	Sulfotransfer_1	67..322	CDD:279075	79/252 (31%)
SULT1B1	XP_005265733.1	Sulfotransfer_1	43..293	CDD:279075	79/252 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157387
Domainoid	1	1.000	149	1.000	Domainoid score	I4409
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H69169
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4327
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49491
OrthoDB	1	1.010	-	-		D481448at33208
OrthoFinder	1	1.000	-	-		FOG0000045
OrthoInspector	1	1.000	-	-		mtm8574
orthoMCL	1	0.900	-	-		OOG6_100094
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.710