DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment St1 and Sult1a1

DIOPT Version :9

Sequence 1:	NP_611815.3	Gene:	St1 / 37742	FlyBaseID:	FBgn0034887	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_598431.2	Gene:	Sult1a1 / 20887	MGIID:	102896	Length:	298	Species:	Mus musculus

Alignment Length:	286	Identity:	90/286 - (31%)
Similarity:	145/286 - (50%)	Gaps:	24/286 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFE 97
            ||.|||.|      ..|...|...::::.:|....|||.|.|.||.|||||.|:..::......:
Mouse    13 KPLVPVKG------IPLIKYFAETMEQLQNFTAWPDDVLISTYPKSGTTWMSEIMDMIYQGGKLD 71

  Fly    98 TAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYR 162
            ......:..|.|||||:  .|.|| ..:......|:||:||:|||..:||:.:..::.|:|||.|
Mouse    72 KCGRAPVYARIPFLEFS--CPGVP-PGLETLKETPAPRIIKTHLPLSLLPQSLLDQKIKVIYVAR 133

  Fly   163 NPKDAAISYFHHWRGMVGYQ---GTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYE 224
            |.||..:||::.:: |....   ||...|:.:|:||.|::...:.|:.::|:||....:.:..||
Mouse   134 NAKDVVVSYYNFYK-MAKLHPDPGTWESFLENFMDGKVSYGSWYQHVKEWWELRRTHPVLYLFYE 197

  Fly   225 RMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFR 289
            .||....:.|.::.:||.||:.:|.:..:..|.||:.|::||..|:        .....||.:..
Mouse   198 DMKENPKREIKKILEFLGRSLPEETVDLIVHHTSFKKMKENPMANY--------TTIPTEVMDHT 254

  Fly   290 ---FVRRGVVGSHKDELTADIIREFD 312
               |:|:|.:|..|:..|......||
Mouse   255 ISPFMRKGTIGDWKNTFTVAQSEHFD 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St1	NP_611815.3	Sulfotransfer_1	67..322	CDD:279075	81/252 (32%)
Sult1a1	NP_598431.2	Sulfotransfer_1	41..291	CDD:366246	81/252 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49491
OrthoDB	1	1.010	-	-		D481448at33208
OrthoFinder	1	1.000	-	-		FOG0000045
OrthoInspector	1	1.000	-	-		otm44260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5797
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.790