Sequence 1: | NP_001163275.2 | Gene: | Pde8 / 37741 | FlyBaseID: | FBgn0266377 | Length: | 1050 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001074.2 | Gene: | PDE5A / 8654 | HGNCID: | 8784 | Length: | 875 | Species: | Homo sapiens |
Alignment Length: | 931 | Identity: | 200/931 - (21%) |
---|---|---|---|
Similarity: | 336/931 - (36%) | Gaps: | 265/931 - (28%) |
- Green bases have known domain annotations that are detailed below.
Fly 222 KGERNHAE--EEPL--TPGHDHEDSVVLRRKVNCLERKAHSLYERRL-PRVPKLHLLVAGKKNPP 281
Fly 282 TEEEEFRTFQRNLMDLKYPTVLPPNPP---------LKALLVFHKSDSICEAITAACQR-----H 332
Fly 333 QL--------------------------DVTLVKSKEEALDTLQK--------SYATAQCYHLII 363
Fly 364 IDARSSKNLDAEHIARTIRHTHGHHLTTII----------------AVCKKS-----FFEKDDVL 407
Fly 408 IALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRI 472
Fly 473 QY-ANRATERLLNMRLDEIIS-KQLE--DIFVSD-------LSTISEQCKNIKEFDGILTVRRKS 526
Fly 527 QEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAP-----RGSLHSVRRCSFD 586
Fly 587 VRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKRE------- 644
Fly 645 ------GLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTAAIVPAKMK 703
Fly 704 SNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDEN-------VCKAW 761
Fly 762 LAVIEAHYRKSNTYHNSTHAADVMQA------TGAFITQLTNKDMLVMDRMEEATALIAAAAHDV 820
Fly 821 DHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFK---LTLGDDKINIFKNLDKETYKSARST 882
Fly 883 IIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQTDEETSILMRRMLIKVADVSNPARPMQFCI 947
Fly 948 EWARRIAEEYFMQTD-EEKQRHLPIVMPMFDRATCSIPKSQIGFIEYI----IQDMMHAWESFID 1007
Fly 1008 MPQLITYMQINYSQWKKYDEQ 1028 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Pde8 | NP_001163275.2 | PAS | 459..539 | CDD:238075 | 19/90 (21%) |
PAS_9 | 463..539 | CDD:290162 | 19/86 (22%) | ||
PDEase_I | 775..1016 | CDD:278654 | 68/254 (27%) | ||
PDE5A | NP_001074.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..29 | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 78..102 | 6/23 (26%) | |||
GAF | 164..321 | CDD:214500 | 33/184 (18%) | ||
GAF | 347..513 | CDD:214500 | 34/205 (17%) | ||
PDEase_I | 612..847 | CDD:278654 | 68/254 (27%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165154168 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D904682at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.850 |