Protein Alignment Pde8 and pde9ac

DIOPT Version :9

• Sequence 1: NP_001163275.2
• Gene: Pde8 / 37741
• FlyBaseID: FBgn0266377
• Length: 1050
• Species: Drosophila melanogaster
• Sequence 2: XP_692819.3
• Gene: pde9ac / 564389
• ZFINID: ZDB-GENE-130530-807
• Length: 558
• Species: Danio rerio
• Alignment Length: 511
• Identity: 146/511 - (28%)
• Similarity: 234/511 - (45%)
• Gaps: 103/511 - (20%)

  Fly   581 RRCS-FDVRSI--ASDGLRRTSLAKLT-----------SLPLEAP--ITKII------------- 616
            |.|| .|::.:  :|..:.|.:...:|           ::|...|  :.|||
Zfish    67 RHCSPCDIKELLCSSSNIPRNTAIMMTDPEGAIVSIDPTMPTNNPNFLYKIIPLSASQLGEKEDM 131

  Fly   617 --NLLSQVQENCS------------ADEARLIDKVLEFLKREGLYSPQMKEIRTD-----DPIAT 662
              |:||||.|..|            .:...:::|.:|.   |||...::::.:.|     |.: |
Zfish   132 FQNVLSQVAEQFSRAFRINELKTEVTNRLAMLEKRVEL---EGLKVVEIEKCKNDMRKLRDEM-T 192

  Fly   663 DLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLE- 726
            ...||.:..|..|:   .|:|     |........:|:..|.. :..|.::......||::..|
Zfish   193 SRAGARVNCPCKYN---FSDD-----GKKLTPRRDIPSYPKYT-LSQETIEALKKPTFDVWHWEH 248

  Fly   727 -EITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGA 790
             |:......:|..:.:.:.|      ||:....|.||..|:.:|| ||.:||..|...|.|....
Zfish   249 NEMLSCLEYMYHDLGLVKEF------NINPITLKRWLLGIQENYR-SNPFHNFRHCFCVSQMMYG 306

  Fly   791 FI------TQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLEN 849
            .|      .:||..|:.::        :.||..||:||||.::.:..|:...|||.|||::.|||
Zfish   307 MIHLCNLQEKLTLTDLGIL--------MTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLEN 363

  Fly   850 HHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDH 914
            ||.|:.|:: |...:.|||.|::.|.:|..|..||.:||||:|.||.|.|..|      :...||
Zfish   364 HHCAVAFQI-LSLPECNIFANVEPEAFKQIRQAIITLILATDMARHGEILDSF------KHKVDH 421

  Fly   915 NPQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRA 979
            ...|:||....::.:|||..|:||..||.:....|...:.||||||:|.||...||:...| ||.
Zfish   422 FDFTNEEHVACLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAAFM-DRE 485

  Fly   980 TCSIPKSQIGFIEYIIQDMMHAWESFIDM-PQLITYM-------QINYSQWKKYDE 1027
            ..:.|.:|||||::::..|   :|:.:.: ||:...|       :.:|.:.|:.|:
Zfish   486 KVTKPTAQIGFIKFVLIPM---FETVMKLFPQIEEIMVQPLRDSRDHYEELKQIDD 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde8	NP_001163275.2	PAS	459..539	CDD:238075
		PAS_9	463..539	CDD:290162
		PDEase_I	775..1016	CDD:278654	90/254 (35%)
pde9ac	XP_692819.3	PDEase_I	291..521	CDD:278654	90/248 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2223
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950