Protein Alignment Pde8 and mapk14

DIOPT Version :9

• Sequence 1: NP_001163275.2
• Gene: Pde8 / 37741
• FlyBaseID: FBgn0266377
• Length: 1050
• Species: Drosophila melanogaster
• Sequence 2: NP_001005824.1
• Gene: mapk14 / 448296
• XenbaseID: XB-GENE-1018617
• Length: 361
• Species: Xenopus tropicalis
• Alignment Length: 492
• Identity: 92/492 - (18%)
• Similarity: 162/492 - (32%)
• Gaps: 197/492 - (40%)

  Fly   575 GSLHSVRRCS-FDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVL 638
            |:..||  || ||.|:..     |.::.||:     .|...||:.....:|.          ::|
 Frog    34 GAYGSV--CSAFDTRTEL-----RVAVKKLS-----RPFQSIIHAKRTYREL----------RLL 76

  Fly   639 EFLKREG------LYSPQMK-EIRTDDPIATDLIGALLTGPSVYSSRRSSND-------SIIRTG 689
            :.:|.|.      :::|... |...|..:.|.|:||.|.  ::...::.::|       .|:|..
 Frog    77 KHMKHENVIGLLDVFTPAKSFEEFNDVYLVTHLMGADLN--NIVKCQKLTDDHVQFLIYQILRGL 139

  Fly   690 SSTRTAAIVPAKMK-SNPII-----MELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVF 748
            ....:|.|:...:| ||..:     :::||..|:...|    ||:|.     |:....:|..::.
 Frog   140 KYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTD----EEMTG-----YVATRWYRAPEIM 195

  Fly   749 ATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALI 813
              ||        |:     ||.::         .|:..........||.:.:.
 Frog   196 --LN--------WM-----HYNQT---------VDIWSVGCIMAELLTGRTLF------------ 224

  Fly   814 AAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKS 878
                     ||....      |.|.::..                .:|..:..:.:.:..|   :
 Frog   225 ---------PGTDHI------DQLKLILR----------------LVGTPEPELLQKISSE---A 255

  Fly   879 ARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQTDEETSILMRRMLIKVADVSNPARPM 943
            ||:.|..:....:|        .|..||.|.     |||..:    |:.:||:...|..
 Frog   256 ARNYIQSLPYMPKM--------NFEDVFLGA-----NPQAVD----LLEKMLVLDTDKR------ 297

  Fly   944 QFCIEWARRIAEEYFMQ---TDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESF 1005
               |..|..:|..||.|   .|:|     ||..| :|:                      ::||
 Frog   298 ---ITAAEALAHPYFAQYHDPDDE-----PIAEP-YDQ----------------------SFES- 330

  Fly  1006 IDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPP 1042
                     .:::..:||:.      |..|::...||
 Frog   331 ---------RELDIEEWKRL------TYEEVICFVPP 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde8	NP_001163275.2	PAS	459..539	CDD:238075
		PAS_9	463..539	CDD:290162
		PDEase_I	775..1016	CDD:278654	38/243 (16%)
mapk14	NP_001005824.1	STKc_p38alpha	7..351	CDD:143382	90/489 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165172331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930