DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pde8 and avd.2

DIOPT Version :9

Sequence 1:	NP_001163275.2	Gene:	Pde8 / 37741	FlyBaseID:	FBgn0266377	Length:	1050	Species:	Drosophila melanogaster
Sequence 2:	XP_002940029.2	Gene:	avd.2 / 100487365	XenbaseID:	XB-GENE-5995460	Length:	153	Species:	Xenopus tropicalis

Alignment Length:	144	Identity:	24/144 - (16%)
Similarity:	50/144 - (34%)	Gaps:	57/144 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   853 AITFKLTLGDDKINIFKNLDKETYKSARSTIIDMIL--------------ATEMTRHFEHLAKFV 903
            |:::.|:..|.:.|:     ..|:.:...:::.::.              .::.....|.:.|.|
Frog    17 AVSYTLSQHDKRCNM-----SGTWVNELGSVLSLVAKGPHLSGSLQSSVETSQGAAGDEKMGKVV 76

  Fly   904 SVFG-GEEP----------------------RDHNPQTDEETSILMRRMLIKVADVSNPARPMQF 945
            .|.| ||:|                      |.:.|        ::|.:.:..::||...:
Frog    77 GVLGDGEQPTFTMSVKWSAGSVSTWAGQCFWRTNCP--------VLRAIWLLRSEVSTEDK---- 129

  Fly   946 CIEW-ARRIAEEYF 958
              .| |.||.|:.|
Frog   130 --NWKATRIGEDLF 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pde8	NP_001163275.2	PAS	459..539	CDD:238075
		PAS_9	463..539	CDD:290162
		PDEase_I	775..1016	CDD:278654	24/144 (17%)
avd.2	XP_002940029.2	Avidin	30..141	CDD:396105	20/129 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165172339
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930