DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and aqp1a.2

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001129154.1	Gene:	aqp1a.2 / 559284	ZFINID:	ZDB-GENE-100409-1	Length:	269	Species:	Danio rerio

Alignment Length:	224	Identity:	73/224 - (32%)
Similarity:	113/224 - (50%)	Gaps:	8/224 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 AFLGELIGTGILVFLGCMGCV--KTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVA 121
            |.|.|.:|..|.||:|....:  |.:.:|:..:::.|.||.|:....|..|.:||||||||:|:.
Zfish    13 AVLAEFVGMTIFVFIGIASAIGNKHNRYPDQEVKVALAFGLAIATLAQSLGHISGAHLNPAITLG 77

  Fly   122 AYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFV 186
            ..:...::...||.|..||||||.:..|::..:.|.|..|:|    :.:....|..||...||..
Zfish    78 LLVSCQISFFRAFMYIIAQMLGAVLASGIMFKVSPDPDTTLG----LNMLGNGVKVGQGFAIELF 138

  Fly   187 ITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESN 251
            .|..||:......|...:....|..:..||::......|..:||..:||||||.||:..:.|:::
Zfish   139 TTFQLVLCALATTDKNRTDVSGSAPLAIGLSVGLGHLVAISYTGCGINPARSFGPAVVLESFKNH 203

  Fly   252 WIYWLAPLSSSAITAYAYKVVF--RREVV 278
            ||||:||:......|..|..:.  :||.:
Zfish   204 WIYWIAPMCGGVAAALIYDFLLFPKREAL 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	71/214 (33%)
aqp1a.2	NP_001129154.1	MIP	4..221	CDD:278651	70/211 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850