DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and MIP

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_036196.1	Gene:	MIP / 4284	HGNCID:	7103	Length:	263	Species:	Homo sapiens

Alignment Length:	211	Identity:	71/211 - (33%)
Similarity:	107/211 - (50%)	Gaps:	3/211 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 AFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAY 123
            |...|...|...||.|....::....|.:.||:.:.||.|:...:|..|.:||||:|||||.|..
Human    12 AIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAMAFGLALATLVQSVGHISGAHVNPAVTFAFL 76

  Fly   124 IYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVIT 188
            :...::|..||.|.|||:|||..|..:|..:.|.   .|...|.:...|.:|:.|||..:|..:|
Human    77 VGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPP---AVRGNLALNTLHPAVSVGQATTVEIFLT 138

  Fly   189 SILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNWI 253
            ...|:.....:|.|.:....||.:..|.::|........:||..||||||||||:...:|.::|:
Human   139 LQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWV 203

  Fly   254 YWLAPLSSSAITAYAY 269
            ||:.|:....:.:..|
Human   204 YWVGPIIGGGLGSLLY 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	71/211 (34%)
MIP	NP_036196.1	MIP	3..219	CDD:333943	70/209 (33%)
		NPA 1	68..70		1/1 (100%)
		NPA 2	184..186		1/1 (100%)
		Interaction with CALM. /evidence=ECO:0000250	227..237
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020