Protein Alignment Eglp4 and AQP9

DIOPT Version :10

• Sequence 1: NP_001261154.1
• Gene: Eglp4 / 37739
• FlyBaseID: FBgn0034885
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_066190.2
• Gene: AQP9 / 366
• HGNCID: 643
• Length: 295
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 97/289 - (33%)
• Similarity: 132/289 - (45%)
• Gaps: 54/289 - (18%)

  Fly    45 KVFKMK---GSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHL--QIVLNFGF--AVLIA 102
            |.||.:   .|:|.|.:  |.|.:||.||:.||| |||...:......  .|.:|.||  ||.:|
Human    10 KSFKQRLVLKSSLAKET--LSEFLGTFILIVLGC-GCVAQAILSRGRFGGVITINVGFSMAVAMA 71

  Fly   103 IQCFGCVSGAHLNPAVTVAAYIY-EMVTLRMAFAYFAAQMLGAFIG--------YGLLMVLLPSP 158
            |...|.|||.|:||||::|..:: .|...::.| |..||.||||:|        |..||......
Human    72 IYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPF-YVGAQFLGAFVGAATVFGIYYDGLMSFAGGK 135

  Fly   159 TLTVG----AGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVG-------I 212
            .|.||    |.:..|.|...::...|...:.|.|.||:|:...::|.||      :|       |
Human   136 LLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRN------LGAPRGLEPI 194

  Fly   213 RFGLAIACLACAAGPFTGGSMNPARSFAPAL------WNKHFE-----SN--WIYWLAPLSSSAI 264
            ..||.|..:|.:.|..:|.:|||||..:|.|      |.  ||     :|  ||..:.||..:.|
Human   195 AIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWG--FEVFRAGNNFWWIPVVGPLVGAVI 257

  Fly   265 TAYAYKVVFRREVVEAEITSNEKLRQLED 293
            ....|.:|.  |:...|..|..|..|.||
Human   258 GGLIYVLVI--EIHHPEPDSVFKTEQSED 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:444743	83/249 (33%)
AQP9	NP_066190.2	GlpF	21..267	CDD:440345	86/259 (33%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:Q96PS8	84..86		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:Q96PS8	216..218		1/1 (100%)