Protein Alignment Eglp4 and AQP5

DIOPT Version :9

• Sequence 1: NP_001261154.1
• Gene: Eglp4 / 37739
• FlyBaseID: FBgn0034885
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001642.1
• Gene: AQP5 / 362
• HGNCID: 638
• Length: 265
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 73/214 - (34%)
• Similarity: 108/214 - (50%)
• Gaps: 4/214 - (1%)

  Fly    57 ISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVA 121
            :.|...|.:.|.|.||.|....:|........|||.|.||.|:....|..|.|||.|:|||:|:|
Human    11 LKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLA 75

  Fly   122 AYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFV 186
            ..:...::|..||.|.|||::||..|.|:|..:.|   |.....|.|...:.:.|.|||:.:|.:
Human    76 LLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAP---LNARGNLAVNALNNNTTQGQAMVVELI 137

  Fly   187 ITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPA-LWNKHFES 250
            :|..|.:......|.|.:....|..:..||::.........|||.||||||||.|| :.|:...:
Human   138 LTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPA 202

  Fly   251 NWIYWLAPLSSSAITAYAY 269
            :|::|:.|:..:.:.|..|
Human   203 HWVFWVGPIVGAVLAAILY 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	73/212 (34%)
AQP5	NP_001642.1	MIP	4..221	CDD:395174	72/212 (34%)
		NPA 1. /evidence=ECO:0000305|PubMed:18768791, ECO:0000305|PubMed:26569106	69..71		1/1 (100%)
		NPA 2. /evidence=ECO:0000305|PubMed:18768791, ECO:0000305|PubMed:26569106	185..187		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140766
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850