Protein Alignment Eglp4 and AQP3

DIOPT Version :9

• Sequence 1: NP_001261154.1
• Gene: Eglp4 / 37739
• FlyBaseID: FBgn0034885
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_004916.1
• Gene: AQP3 / 360
• HGNCID: 636
• Length: 292
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 86/273 - (31%)
• Similarity: 123/273 - (45%)
• Gaps: 50/273 - (18%)

  Fly    61 LGELIGTGILVFLGCMGCVKTDLFPNNH---LQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVA- 121
            |.|.:||.|||..||....:..|....|   |.|.|.|||||.:.|...|.|||||||||||.|
Human    26 LAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAM 90

  Fly   122 AYIYEMVTLRMAFAYFAAQMLGAFIGYGL----------------LMVLLPSPTLTVGAGLCVTL 170
            .::.....:::.. |..||.||||:|.|:                |.|..|:.|    ||:..|.
Human    91 CFLAREPWIKLPI-YTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGT----AGIFATY 150

  Fly   171 P--HTSVTTG---QALGIEFVITSILVIVCCGVWDPRNSKFHDSV-GIRFGLAIACLACAAGPFT 229
            |  |..:..|   |.:|...:|..:|.||     ||.|:.....: ....||.:..:..:.|..:
Human   151 PSGHLDMINGFFDQFIGTASLIVCVLAIV-----DPYNNPVPRGLEAFTVGLVVLVIGTSMGFNS 210

  Fly   230 GGSMNPARSFAPAL------WNKH-FESNWIYWLAPLSSSAITAYAYKVVFRREV---VEAEITS 284
            |.::||||.|.|.|      |... |.:...:|..|:.|..:.:.|...|::..:   :|....|
Human   211 GYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPS 275

  Fly   285 NEKLRQLEDVQLS 297
            ||:    |:|:|:
Human   276 NEE----ENVKLA 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	78/243 (32%)
AQP3	NP_004916.1	MIP	23..264	CDD:238204	79/247 (32%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:Q96PS8	83..85		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:Q96PS8	215..217		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140753
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100415
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X153
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.650