Protein Alignment Eglp4 and AQP2

DIOPT Version :9

• Sequence 1: NP_001261154.1
• Gene: Eglp4 / 37739
• FlyBaseID: FBgn0034885
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_000477.1
• Gene: AQP2 / 359
• HGNCID: 634
• Length: 271
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 73/215 - (33%)
• Similarity: 107/215 - (49%)
• Gaps: 5/215 - (2%)

  Fly    59 AFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAY 123
            |...|.:.|.:.||.|....:.......:.|||.:.||..:...:|..|.:||||:|||||||..
Human    12 AVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHINPAVTVACL 76

  Fly   124 I-YEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVI 187
            : ..:..||.|| |.|||:|||..|..||..:.|:   .:...|.|.....|.|.|||:.:|..:
Human    77 VGCHVSVLRAAF-YVAAQLLGAVAGAALLHEITPA---DIRGDLAVNALSNSTTAGQAVTVELFL 137

  Fly   188 TSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNW 252
            |..||:......|.|..:...:..:..|.::|........:||.|||||||.|||:....|:.:|
Human   138 TLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHW 202

  Fly   253 IYWLAPLSSSAITAYAYKVV 272
            ::|:.||..:.:.:..|..|
Human   203 VFWIGPLVGAILGSLLYNYV 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	72/213 (34%)
AQP2	NP_000477.1	MIP	3..219	CDD:278651	71/210 (34%)
		NPA 1. /evidence=ECO:0000305|PubMed:24733887	68..70		1/1 (100%)
		NPA 2. /evidence=ECO:0000305|PubMed:24733887	184..186		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	248..271

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140757
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850