DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and Aqp2

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_037041.3	Gene:	Aqp2 / 25386	RGDID:	2142	Length:	271	Species:	Rattus norvegicus

Alignment Length:	212	Identity:	77/212 - (36%)
Similarity:	109/212 - (51%)	Gaps:	5/212 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 AFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAY 123
            |.|.|.:.|.:.||.|....::....|.:.|||.:.||..:...:|..|.|||||:|||||||..
  Rat    12 AVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGTLVQALGHVSGAHINPAVTVACL 76

  Fly   124 IYEMVT-LRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVI 187
            :...|: ||.|| |.|||:|||..|..:|..:.|   :.:...|.|...|.:.|.|||:.:|..:
  Rat    77 VGCHVSFLRAAF-YVAAQLLGAVAGAAILHEITP---VEIRGDLAVNALHNNATAGQAVTVELFL 137

  Fly   188 TSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNW 252
            |..||:......|.|......|..:..|.::.........|||.|||||||.|||:....|:.:|
  Rat   138 TMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHW 202

  Fly   253 IYWLAPLSSSAITAYAY 269
            ::|:.||..:.|.:..|
  Rat   203 VFWIGPLVGAIIGSLLY 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	77/212 (36%)
Aqp2	NP_037041.3	MIP	3..219	CDD:395174	76/210 (36%)
		NPA 1. /evidence=ECO:0000250\|UniProtKB:P41181	68..70		1/1 (100%)
		NPA 2. /evidence=ECO:0000250\|UniProtKB:P41181	184..186		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950