DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and AgaP_AGAP010325

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	XP_318238.4	Gene:	AgaP_AGAP010325 / 1278605	VectorBaseID:	AGAP010325	Length:	264	Species:	Anopheles gambiae

Alignment Length:	235	Identity:	132/235 - (56%)
Similarity:	174/235 - (74%)	Gaps:	7/235 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 MKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAH 113
            ||.||||.||.||.||||||:||.|||||||.......:|.::.:|||..|:|.:|.||||||:|
Mosquito    12 MKKSTLDNISVFLAELIGTGLLVMLGCMGCVSGLGHTPSHFELCINFGLIVMIIVQIFGCVSGSH 76

  Fly   114 LNPAVTVAAYIYEMVTLRMA--FAYFAAQMLGAFIGYGLLMVLLPSPTLTV----GAGLCVTLPH 172
            ||||||.||::||:|:.::.  |..| :|.:|||:|||:|.:|.|:....|    |||.|||.|:
Mosquito    77 LNPAVTAAAWVYELVSTKVGALFLIF-SQCIGAFMGYGILKLLTPASVFDVALEKGAGFCVTQPN 140

  Fly   173 TSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPAR 237
            ::::..||:|||||.|.:|::||||||||||:|.||||.::||..:..||.||||:||.||||||
Mosquito   141 SAISNMQAVGIEFVATMVLILVCCGVWDPRNAKHHDSVALKFGFTVGALAVAAGPYTGASMNPAR 205

  Fly   238 SFAPALWNKHFESNWIYWLAPLSSSAITAYAYKVVFRREV 277
            |..|.|||..:.::||||:.||.::.:||:|||.||||||
Mosquito   206 SLGPVLWNGVYNAHWIYWVGPLGAAFLTAFAYKAVFRREV 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	118/218 (54%)
AgaP_AGAP010325	XP_318238.4	MIP	15..237	CDD:294134	121/222 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136579
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26905
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19139
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880