DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and Aqp8

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_031500.1	Gene:	Aqp8 / 11833	MGIID:	1195271	Length:	261	Species:	Mus musculus

Alignment Length:	218	Identity:	67/218 - (30%)
Similarity:	109/218 - (50%)	Gaps:	10/218 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 CKVFKMKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNH-LQIVLNFGFAVLIAIQCFG 107
            |:||..:    ..:...:.||:|:.:.:|:||:..::..  ||.. ||..|..|.|:.:.|...|
Mouse    26 CRVFWYE----QYVQPCIVELVGSALFIFIGCLSVIENS--PNTGLLQPALAHGLALGLIIATLG 84

  Fly   108 CVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPH 172
            .:||.|.||||::|..:...:...:...|:.:|:.|..||..|..|:.|.......:|....:..
Mouse    85 NISGGHFNPAVSLAVTVIGGLKTMLLIPYWISQLFGGLIGAALAKVVSPEERFWNASGAAFAIVQ 149

  Fly   173 TSVTTGQALGIEFVITSILVI-VCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPA 236
            ......:|||||.::|.:||: ||.|..:.:.........|.|.:.:..|  |.|..:|..||||
Mouse   150 EQEQVAEALGIEIILTMLLVLAVCMGAVNEKTMGPLAPFSIGFSVIVDIL--AGGSISGACMNPA 212

  Fly   237 RSFAPALWNKHFESNWIYWLAPL 259
            |:|.||:...:::.:|||||.||
Mouse   213 RAFGPAVMAGYWDFHWIYWLGPL 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	64/203 (32%)
Aqp8	NP_031500.1	MIP	38..248	CDD:294134	64/202 (32%)
		NPA 1	92..94		1/1 (100%)
		NPA 2	210..212		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830757
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750