DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and Aqp7

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001365567.1	Gene:	Aqp7 / 11832	MGIID:	1314647	Length:	316	Species:	Mus musculus

Alignment Length:	219	Identity:	57/219 - (26%)
Similarity:	93/219 - (42%)	Gaps:	21/219 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 STLDK--ISAFLGELIGTGILVFLGCMGCVKTDLFPNN---HLQIVLNFGFAVLIAIQCFGCVSG 111
            |.|.|  :..||.|.:.|.:::..| :|.|...:...|   :|.:.|.|||.|.:.:...|.:||
Mouse    12 SVLQKNMVREFLAEFLSTYVMMVFG-LGSVAHMVLGENSGSYLGVNLGFGFGVTMGVHVAGGISG 75

  Fly   112 AHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAF--------IGYGLLMVLLPSPTLTVG----A 164
            ||:|.|||........:|.:....|...|.||:|        |.||.:........|..|    |
Mouse    76 AHMNAAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATA 140

  Fly   165 GLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNS-KFHDSVGIRFGLAIACLACAAGPF 228
            .:..|.....:|..:....|..:|.:|.:....:.|.:|| ....:..:..|:.:..|..:.|..
Mouse   141 NIFATYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMN 205

  Fly   229 TGGSMNPARSFAPALWNKHFESNW 252
            :|.::||:|...|.|:.  |.:.|
Mouse   206 SGYAINPSRDLPPRLFT--FIAGW 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	54/210 (26%)
Aqp7	NP_001365567.1	MIP	18..232	CDD:412216	54/213 (25%)
		NPA 1	79..81		1/1 (100%)
		NPA 2	211..213		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X153
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740