DRSC/TRiP Functional Genomics Resources

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Protein Alignment Eglp4 and Aqp5

DIOPT Version :9

Sequence 1:NP_001261154.1 Gene:Eglp4 / 37739 FlyBaseID:FBgn0034885 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_033831.1 Gene:Aqp5 / 11830 MGIID:106215 Length:265 Species:Mus musculus


Alignment Length:241 Identity:77/241 - (31%)
Similarity:109/241 - (45%) Gaps:27/241 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 SVALFKRFSDHFSCCKVFKMKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLN 94
            |||.||                       |...|.:.|.|.||.|....:|........|||.:.
Mouse     7 SVAFFK-----------------------AVFAEFLATLIFVFFGLGSALKWPSALPTILQISIA 48

  Fly    95 FGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPT 159
            ||.|:....|..|.|||.|:|||:|:|..|...::|..|..|.|||::||..|.|:|..|.|.  
Mouse    49 FGLAIGTLAQALGPVSGGHINPAITLALLIGNQISLLRAIFYVAAQLVGAIAGAGILYWLAPG-- 111

  Fly   160 LTVGAGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACA 224
             .....|.|.....:.|.|:|:.:|.::|..|.:......|.|.:....|..:..||::......
Mouse   112 -NARGNLAVNALSNNTTPGKAVVVELILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLV 175

  Fly   225 AGPFTGGSMNPARSFAPA-LWNKHFESNWIYWLAPLSSSAITAYAY 269
            ...|||.||||||||.|| :.|:...|:|::|:.|:..:.:.|..|
Mouse   176 GIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAVLAAILY 221

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Eglp4NP_001261154.1 MIP 59..272 CDD:294134 72/212 (34%)
Aqp5NP_033831.1 MIP 4..221 CDD:278651 76/239 (32%)
NPA 1. /evidence=ECO:0000250|UniProtKB:P55064 69..71 1/1 (100%)
NPA 2. /evidence=ECO:0000250|UniProtKB:P55064 185..187 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167830739
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0580
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1152704at2759
OrthoFinder 1 1.000 - - FOG0000054
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19139
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.850

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