DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and aqp8

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001107728.1	Gene:	aqp8 / 100135726	XenbaseID:	XB-GENE-481926	Length:	269	Species:	Xenopus tropicalis

Alignment Length:	212	Identity:	61/212 - (28%)
Similarity:	101/212 - (47%)	Gaps:	18/212 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIY 125
            :.||:|:.:.:|.||:..:: :......||..|..|.|:.:.|...|.:||.|.||||::||::.
Frog    49 VAELLGSALFIFAGCLSVIE-NASTTGSLQPALAHGLALGLTIAVLGGISGGHFNPAVSLAAWLI 112

  Fly   126 EMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVITSI 190
            ..:.:.:...|:..|:.|..||..|.|.:..........|...|......:..:|:|.|.::|..
Frog   113 GGLNIILLVPYWVCQLCGGMIGAALAMAVSADTNFENATGAAFTTVKNDESVARAIGAEIIMTFF 177

  Fly   191 LVI-VCCGVWDPRNSKFHDSVGIRFGLAIACLA-------CAAGPFTGGSMNPARSFAPALWNKH 247
            ||. ||.|..:.::         |..||..|:.       .|.|..:|..|||||:|.||:...:
Frog   178 LVFAVCMGAINEKS---------RTPLAPFCIGFTVTVDILAGGAISGACMNPARAFGPAVVADY 233

  Fly   248 FESNWIYWLAPLSSSAI 264
            :..:||||:.||:...:
Frog   234 WTFHWIYWVGPLAGGLL 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	61/212 (29%)
aqp8	NP_001107728.1	MIP	48..258	CDD:294134	61/212 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4373
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970