DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp4 and aqp10b

DIOPT Version :9

Sequence 1:	NP_001261154.1	Gene:	Eglp4 / 37739	FlyBaseID:	FBgn0034885	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	XP_005159449.1	Gene:	aqp10b / 100034395	ZFINID:	ZDB-GENE-060503-57	Length:	309	Species:	Danio rerio

Alignment Length:	230	Identity:	58/230 - (25%)
Similarity:	97/230 - (42%)	Gaps:	25/230 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LGELIGTGILVFLGCMGCVKTDLFPN---NHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAA 122
            |.|..|..:|:..||....:.....|   .:|.|.|.|.......|.....||||||||||:|:.
Zfish    19 LAEFFGVYVLILFGCGSVAQVTTSQNTKGEYLSINLGFALGTTFGIYIAKGVSGAHLNPAVSVSL 83

  Fly   123 YIYEMVT-LRMAFAYFAAQMLGAFIG--------YGLLMVL----LPSPTLTVGAGLCVTLPHTS 174
            .:....: .|:.| |..:|:.|||:.        |..:|..    |.....|..||:..|.|...
Zfish    84 CVLGRFSWTRLPF-YVCSQLFGAFLAAATVALQYYDAIMDFTGGHLTVSGATATAGIFSTYPADY 147

  Fly   175 VTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSV-GIRFGLAIACLACAAGPFTGGSMNPARS 238
            ::....:..:.:.|:.|::....:.|..|:.....: .:..|.|:..:..:.|..:|.::||||.
Zfish   148 LSLWGGVVDQIIGTAALLVCVLALGDAHNTPAPAGLEPVLVGAAVLVIGISMGSNSGYAINPARD 212

  Fly   239 FAPAL------W-NKHFESNWIYWLAPLSSSAITA 266
            |.|.|      | ::.|.:...:|..|:..:.:.|
Zfish   213 FGPRLFSYIAGWGDEVFRAGHGWWWVPIIVTCVGA 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp4	NP_001261154.1	MIP	59..272	CDD:294134	58/230 (25%)
aqp10b	XP_005159449.1	MIP	5..247	CDD:294134	57/228 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100415
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X153
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.640