DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp3 and AQY1

DIOPT Version :9

Sequence 1:	NP_611812.2	Gene:	Eglp3 / 37738	FlyBaseID:	FBgn0034884	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_015518.1	Gene:	AQY1 / 856322	SGDID:	S000006396	Length:	305	Species:	Saccharomyces cerevisiae

Alignment Length:	246	Identity:	71/246 - (28%)
Similarity:	117/246 - (47%)	Gaps:	34/246 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ARWRLEGHQRSAIACFFGELAATAVFVFIACMGC---------VETPLFQNSH----FRSGLTFG 66
            :|..|..|..:|:    ||...|.:|::.|.:.|         |..|  ..||    ....:.||
Yeast    41 SRDTLRDHFIAAV----GEFCGTFMFLWCAYVICNVANHDVALVAAP--DGSHPGQLIMIAIGFG 99

  Fly    67 LAILIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIK 131
            .:::.:|.||..|||..||||::|:..|..|:...|.:..:|:|....:...|...|:.||..:
Yeast   100 FSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVL- 163

  Fly   132 GVDNPSGVCVTILAPGISVLQGVFIEFLITC--CLVMVACSVWDPRNAKLQDSVPVRFGLTVSCL 194
             ..|..|:       |.|..:|:|:|...|.  ||.::..:| :.|......::|:...|.::.:
Yeast   164 -FANSLGL-------GCSRTRGLFLEMFGTAILCLTVLMTAV-EKRETNFMAALPIGISLFIAHV 219

  Fly   195 ILTAGLFTGASMNPTRSLGPAVWNDSWAH-HWIYWVGPLVAGAVTSLIYRM 244
            .|||  :||..:||.||||.||....:.| |||||:|.|:...:...::::
Yeast   220 ALTA--YTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQL 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	67/229 (29%)
AQY1	NP_015518.1	MIP	54..266	CDD:273306	67/225 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I1786
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1546
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		mtm13431
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.890