DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp3 and Aqp9

DIOPT Version :9

Sequence 1:	NP_611812.2	Gene:	Eglp3 / 37738	FlyBaseID:	FBgn0034884	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001258772.1	Gene:	Aqp9 / 64008	MGIID:	1891066	Length:	321	Species:	Mus musculus

Alignment Length:	232	Identity:	65/232 - (28%)
Similarity:	107/232 - (46%)	Gaps:	35/232 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 FIACMGCVETPLFQNSHFRSG------LTFGLAILIAIQCFGSVSGAHLNPAITLAAWLYGAIGW 100
            |...:||........|..::|      :.|..|:::|:.....|||.|:|||::.|...:|.:.|
Mouse    61 FYLVLGCGSIAQAVLSREKAGGIITINIGFATAVVMALYATFGVSGGHINPAVSFAMCTFGRMEW 125

  Fly   101 IRAIAYFVAQAAGALIG--------YGLLVAVLPGN-SIKGVDNPSGVCVTILAPGISVLQGVFI 156
            .:...|..||..||.:|        |..|:|...|. .|.|.:..:.:..|...|.:|| .|.|:
Mouse   126 FKFPFYVGAQLLGAFVGAATVFGIYYDGLMAFADGKLLITGENGTAFIFATYPKPFVSV-PGAFV 189

  Fly   157 EFLI-TCCLVMVACSVWDPRNAKLQDSV-PVRFGLTVSCLILTAGLFTGASMNPTRSLGP----- 214
            :.:: |..|:::..:::|.||..:...: |:..||.:..:..:.||.:|.:|||.|.|.|
Mouse   190 DQVVSTMFLLLIVFAIFDSRNLGVPRGLEPIVIGLLIIVISCSLGLNSGCAMNPARDLSPRLFTA 254

  Fly   215 -AVW--------NDSWAHHWIYWVGPLVAGAVTSLIY 242
             |.|        |:.|   ||..|||::...:..|||
Mouse   255 LAGWGFEVFTFGNNFW---WIPVVGPMIGAVLGGLIY 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	65/232 (28%)
Aqp9	NP_001258772.1	MIP	<61..292	CDD:294134	65/232 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100415
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X153
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.650