DRSC/TRiP Functional Genomics Resources

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Protein Alignment Eglp3 and MIP

DIOPT Version :9

Sequence 1:NP_611812.2 Gene:Eglp3 / 37738 FlyBaseID:FBgn0034884 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_036196.1 Gene:MIP / 4284 HGNCID:7103 Length:263 Species:Homo sapiens


Alignment Length:232 Identity:76/232 - (32%)
Similarity:117/232 - (50%) Gaps:20/232 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 WRLEGHQRSAI--ACFFGELAATAVFVFI---ACMGCVETPLFQNSH-FRSGLTFGLAILIAIQC 75
            |.|    |||.  ...|.|..||..:||.   :.:.....||    | .:..:.||||:...:|.
Human     2 WEL----RSASFWRAIFAEFFATLFYVFFGLGSSLRWAPGPL----HVLQVAMAFGLALATLVQS 58

  Fly    76 FGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIKGVDNPSGVC 140
            .|.:||||:|||:|.|..:...:..:||..|..||..||:.|..:|.:|.| .:::|     .:.
Human    59 VGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTP-PAVRG-----NLA 117

  Fly   141 VTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQDSVPVRFGLTVSCLILTAGLFTGAS 205
            :..|.|.:||.|...:|..:|...|:...:.:|.|......||.:..|.:::...|....:|||.
Human   118 LNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAG 182

  Fly   206 MNPTRSLGPAVWNDSWAHHWIYWVGPLVAGAVTSLIY 242
            |||.||..||:...::.:||:|||||::.|.:.||:|
Human   183 MNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLY 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Eglp3NP_611812.2 MIP 30..244 CDD:294134 71/217 (33%)
MIPNP_036196.1 MIP 3..219 CDD:333943 74/229 (32%)
NPA 1 68..70 1/1 (100%)
NPA 2 184..186 1/1 (100%)
Interaction with CALM. /evidence=ECO:0000250 227..237
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1152704at2759
OrthoFinder 1 1.000 - - FOG0000054
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19139
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
44.020

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