Protein Alignment Eglp3 and AQP5

DIOPT Version :9

• Sequence 1: NP_611812.2
• Gene: Eglp3 / 37738
• FlyBaseID: FBgn0034884
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001642.1
• Gene: AQP5 / 362
• HGNCID: 638
• Length: 265
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 77/213 - (36%)
• Similarity: 107/213 - (50%)
• Gaps: 7/213 - (3%)

  Fly    31 FGELAATAVFVFIACMGCVETPLFQNSHFRSGLTFGLAILIAIQCFGSVSGAHLNPAITLAAWLY 95
            |.|..||.:|||......::.|....:..:..|.|||||....|..|.|||.|:|||||||..:.
Human    15 FAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVG 79

  Fly    96 GAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIKGVDNPSGVCVTILAPGISVLQGVFIEFLI 160
            ..|..:||..|..||..||:.|.|:|..|.|.|: :|     .:.|..|....:..|.:.:|.::
Human    80 NQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNA-RG-----NLAVNALNNNTTQGQAMVVELIL 138

  Fly   161 TCCLVMVACSVWDPRNAKLQDSVPVRFGLTVSCLILTAGLFTGASMNPTRSLGPA-VWNDSWAHH 224
            |..|.:...:..|.|......|..:..||:|:...|....|||.||||.||.||| |.|.....|
Human   139 TFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAH 203

  Fly   225 WIYWVGPLVAGAVTSLIY 242
            |::||||:|...:.:::|
Human   204 WVFWVGPIVGAVLAAILY 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	77/213 (36%)
AQP5	NP_001642.1	MIP	4..221	CDD:395174	76/211 (36%)
		NPA 1. /evidence=ECO:0000305|PubMed:18768791, ECO:0000305|PubMed:26569106	69..71		1/1 (100%)
		NPA 2. /evidence=ECO:0000305|PubMed:18768791, ECO:0000305|PubMed:26569106	185..187		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140768
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850