Protein Alignment Eglp3 and AQP4

DIOPT Version :9

• Sequence 1: NP_611812.2
• Gene: Eglp3 / 37738
• FlyBaseID: FBgn0034884
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001304313.1
• Gene: AQP4 / 361
• HGNCID: 637
• Length: 352
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 81/232 - (34%)
• Similarity: 121/232 - (52%)
• Gaps: 12/232 - (5%)

  Fly    33 ELAATAVFVFIAC-----MGCVETPLFQNSHFRSGLTFGLAILIAIQCFGSVSGAHLNPAITLAA 92
            |..|..:||.::.     .|..|.||..:....| |.|||:|...:||||.:||.|:|||:|:|.
Human    41 EFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLIS-LCFGLSIATMVQCFGHISGGHINPAVTVAM 104

  Fly    93 WLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIKGVDNPSGVCVTILAPGISVLQGVFIE 157
            .....|...:::.|..||..||:||.|:|..|.|.:.:      .|:.||::...::...|:.:|
Human   105 VCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVV------GGLGVTMVHGNLTAGHGLLVE 163

  Fly   158 FLITCCLVMVACSVWDPRNAKLQDSVPVRFGLTVSCLILTAGLFTGASMNPTRSLGPAVWNDSWA 222
            .:||..||....:..|.:...:..|:.:..|.:|:...|.|..:|||||||.||.||||...:|.
Human   164 LIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWE 228

  Fly   223 HHWIYWVGPLVAGAVTSLIYRMAFKGDEEIDLRTSDA 259
            :||||||||::...:...:|...|..|.|...|..:|
Human   229 NHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEA 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	76/215 (35%)
AQP4	NP_001304313.1	MIP	31..248	CDD:278651	75/213 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850