Protein Alignment Eglp3 and AQP3

DIOPT Version :9

• Sequence 1: NP_611812.2
• Gene: Eglp3 / 37738
• FlyBaseID: FBgn0034884
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_004916.1
• Gene: AQP3 / 360
• HGNCID: 636
• Length: 292
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 79/301 - (26%)
• Similarity: 128/301 - (42%)
• Gaps: 55/301 - (18%)

  Fly     1 MSQQKQKSQESNP--NARWRLEGHQRSAIACFFGELAATAVFVFIACMGCVETPLFQNSH---FR 60
            |.:||:.......  :.|:||   .|.|:|    |...|.:.|...|....:..|.:.:|   ..
Human     1 MGRQKELVSRCGEMLHIRYRL---LRQALA----ECLGTLILVMFGCGSVAQVVLSRGTHGGFLT 58

  Fly    61 SGLTFGLAILIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAV- 124
            ..|.||.|:.:.|...|.|||||||||:|.|........||:...|.:||..||.:|.|::..:
Human    59 INLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLY 123

  Fly   125 ------LPGNS--IKGVDNPSGVCVTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQD 181
                  ...|.  :.|.:..:|:..|..:..:.::.|.|.:|:.|..|::...::.||.|.
Human   124 YDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNN---- 184

  Fly   182 SVPVRFGL---TVSCLIL----TAGLFTGASMNPTRSLGP------AVWND---SWAHHWIYW-- 228
              ||..||   ||..::|    :.|..:|.::||.|..||      |.|..   :...|| :|
Human   185 --PVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHW-WWVP 246

  Fly   229 -VGPLVAGAVTSLIYRMAF--------KGDEEIDLRTSDAK 260
             |.||:.......:|::..        ..:||.:::.:..|
Human   247 IVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVK 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	67/244 (27%)
AQP3	NP_004916.1	MIP	23..264	CDD:238204	70/251 (28%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:Q96PS8	83..85		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:Q96PS8	215..217		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140755
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.869916	Normalized mean entropy	S1906
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100415
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X153
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.630