Protein Alignment Eglp3 and AQP8

DIOPT Version :9

• Sequence 1: NP_611812.2
• Gene: Eglp3 / 37738
• FlyBaseID: FBgn0034884
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: XP_011544124.1
• Gene: AQP8 / 343
• HGNCID: 642
• Length: 262
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 91/264 - (34%)
• Similarity: 131/264 - (49%)
• Gaps: 28/264 - (10%)

  Fly     7 KSQESNPNARWRLEGHQRSAIACFFGELAATAVFVFIACMGCVE----TPLFQNSHFRSGLTFGL 67
            |::|.:...|||:..::|....|.. ||..:|:|:||.|:..:|    |.|.|     ..|..||
Human    17 KAREPSVGGRWRVSWYERFVQPCLV-ELLGSALFIFIGCLSVIENGTDTGLLQ-----PALAHGL 75

  Fly    68 AILIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIKG 132
            |:.:.|...|::||.|.|||::|||.|.|.:..:..:.|:|:|..|.::|..|..||.|.....
Human    76 ALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFW- 139

  Fly   133 VDNPSGVC-VTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQDSV-PVRFGLTVSCLI 195
              |.||.. ||:...| .|...:..|.::|..|.:..|  ....|.|.:..: |...|..|:..|
Human   140 --NASGAAFVTVQEQG-QVAGALVAEIILTTLLALAVC--MGAINEKTKGPLAPFSIGFAVTVDI 199

  Fly   196 LTAGLFTGASMNPTRSLGPAVWNDSWAHHWIYWVGPLVAGAVTSLIYRMAFKGDEEIDLRTSDAK 260
            |..|..:|..|||.|:.||||..:.|..|||||:|||:||.:..|:.| .|.|         |.|
Human   200 LAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLLIR-CFIG---------DGK 254

  Fly   261 IRMI 264
            .|:|
Human   255 TRLI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	77/219 (35%)
AQP8	XP_011544124.1	MIP	39..232	CDD:294134	70/204 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140794
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4525
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.830