DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eglp3 and aqp1a.1

DIOPT Version :9

Sequence 1:	NP_611812.2	Gene:	Eglp3 / 37738	FlyBaseID:	FBgn0034884	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_996942.1	Gene:	aqp1a.1 / 335821	ZFINID:	ZDB-GENE-030131-7764	Length:	260	Species:	Danio rerio

Alignment Length:	244	Identity:	83/244 - (34%)
Similarity:	119/244 - (48%)	Gaps:	28/244 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSQQKQKSQESNPNARWRLEGHQRSAIACFFGELAATAVFVFIACMGCVETPLFQN--SHFRSGL 63
            |::.|.|       |.||          ....||....:|:|::....|.....||  ...:..|
Zfish     1 MNELKSK-------AFWR----------AVLAELLGMTLFIFLSITAAVGNTNTQNPDQEIKVAL 48

  Fly    64 TFGLAILIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGN 128
            .|||:|....|..|.:||||||||:||.......|..:||:.|.:||..||.:...:::.|..|:
Zfish    49 AFGLSIATLAQSLGHISGAHLNPAVTLGLLASCQISLLRAVMYILAQMIGATVASAIVLGVSKGD 113

  Fly   129 SIKGVDNPSGVCVTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQDSVPVRFGLTVSC 193
            :: |::.        :...||..|||.||.|.|..||:...:..|.|...:..|.|:..||:|..
Zfish   114 AL-GLNQ--------IHTDISAGQGVGIELLATFQLVLCVLATTDKRRRDVSGSAPLAIGLSVCL 169

  Fly   194 LILTAGLFTGASMNPTRSLGPAVWNDSWAHHWIYWVGPLVAGAVTSLIY 242
            ..|||..|||..:||.|:.|||:....:|:||:|||||:..|...:|||
Zfish   170 GHLTAISFTGCGINPARTFGPAMIRLDFANHWVYWVGPMCGGVAAALIY 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	77/215 (36%)
aqp1a.1	NP_996942.1	MIP	3..218	CDD:278651	80/240 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573511
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.880