DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp3 and Mip

DIOPT Version :9

Sequence 1:	NP_611812.2	Gene:	Eglp3 / 37738	FlyBaseID:	FBgn0034884	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001099189.1	Gene:	Mip / 25480	RGDID:	3090	Length:	263	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	77/232 - (33%)
Similarity:	118/232 - (50%)	Gaps:	20/232 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 WRLEGHQRSAI--ACFFGELAATAVFVFI---ACMGCVETPLFQNSH-FRSGLTFGLAILIAIQC 75
            |.|    |||.  ...|.|..||..:||.   :.:.....||    | .:..|.||||:...:|.
  Rat     2 WEL----RSASFWRAIFAEFFATLFYVFFGLGSSLRWAPGPL----HVLQVALAFGLALATLVQT 58

  Fly    76 FGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIKGVDNPSGVC 140
            .|.:||||:|||:|.|..:...:..:||..|..||..||:.|..:|.:|.| .:::|     .:.
  Rat    59 VGHISGAHVNPAVTFAFLVGSQMSLLRAFCYIAAQLLGAVAGAAVLYSVTP-PAVRG-----NLA 117

  Fly   141 VTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQDSVPVRFGLTVSCLILTAGLFTGAS 205
            :..|..|:||.|...:|..:|...|:...:.:|.|......||.:..|.:::...|....:|||.
  Rat   118 LNTLHAGVSVGQATTVEIFLTLQFVLCIFATYDERRNGRMGSVALAVGFSLTLGHLFGMYYTGAG 182

  Fly   206 MNPTRSLGPAVWNDSWAHHWIYWVGPLVAGAVTSLIY 242
            |||.||..||:...::::||:|||||::.|.:.||:|
  Rat   183 MNPARSFAPAILTRNFSNHWVYWVGPIIGGGLGSLLY 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	72/217 (33%)
Mip	NP_001099189.1	MIP	3..219	CDD:278651	75/229 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334479
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850