DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp3 and Aqp7

DIOPT Version :9

Sequence 1:	NP_611812.2	Gene:	Eglp3 / 37738	FlyBaseID:	FBgn0034884	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001365567.1	Gene:	Aqp7 / 11832	MGIID:	1314647	Length:	316	Species:	Mus musculus

Alignment Length:	207	Identity:	51/207 - (24%)
Similarity:	96/207 - (46%)	Gaps:	12/207 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QRSAIACFFGELAATAVFVFIACMGCVETPLFQN--SHFRSGLTFGLAILIAIQCFGSVSGAHLN 85
            |::.:..|..|..:|.|.:...........|.:|  |:....|.||..:.:.:...|.:||||:|
Mouse    15 QKNMVREFLAEFLSTYVMMVFGLGSVAHMVLGENSGSYLGVNLGFGFGVTMGVHVAGGISGAHMN 79

  Fly    86 PAITLAAWLYGAIGWIRAIAYFVAQAAGA--------LIGYGLLVAVLPGN-SIKGVDNPSGVCV 141
            .|:|......|.:.|.:...|.:.|..|:        ||.||.:.....|: .:.|....:.:..
Mouse    80 AAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFA 144

  Fly   142 TILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNA-KLQDSVPVRFGLTVSCLILTAGLFTGAS 205
            |.|...:::.:|...|..:|..|.:...::.|.:|: .||.:.|:..|:.|:.|.::.|:.:|.:
Mouse   145 TYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYA 209

  Fly   206 MNPTRSLGPAVW 217
            :||:|.|.|.::
Mouse   210 INPSRDLPPRLF 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	50/200 (25%)
Aqp7	NP_001365567.1	MIP	18..232	CDD:412216	50/204 (25%)
		NPA 1	79..81		1/1 (100%)
		NPA 2	211..213		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830746
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X153
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.770