DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp3 and aqp8

DIOPT Version :9

Sequence 1:	NP_611812.2	Gene:	Eglp3 / 37738	FlyBaseID:	FBgn0034884	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001107728.1	Gene:	aqp8 / 100135726	XenbaseID:	XB-GENE-481926	Length:	269	Species:	Xenopus tropicalis

Alignment Length:	252	Identity:	87/252 - (34%)
Similarity:	131/252 - (51%)	Gaps:	17/252 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KQKSQESNPNARWRLEGHQRSAIACFFGELAATAVFVFIACMGCVETPLFQNSHFRSGLTFGLAI 69
            |:::.:.:|:  | .|.:.:..:|    ||..:|:|:|..|:..:|......| .:..|..|||:
Frog    30 KEEAVDISPH--W-FETYVQPCVA----ELLGSALFIFAGCLSVIENASTTGS-LQPALAHGLAL 86

  Fly    70 LIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIKGVD 134
            .:.|...|.:||.|.|||::|||||.|.:..|..:.|:|.|..|.:||..|.:||   ::....:
Frog    87 GLTIAVLGGISGGHFNPAVSLAAWLIGGLNIILLVPYWVCQLCGGMIGAALAMAV---SADTNFE 148

  Fly   135 NPSGVCVTILAPGISVLQGVFIEFLITCCLVMVAC--SVWDPRNAKLQDSVPVRFGLTVSCLILT 197
            |.:|...|.:....||.:.:..|.::|..||...|  ::.:.....|   .|...|.||:..||.
Frog   149 NATGAAFTTVKNDESVARAIGAEIIMTFFLVFAVCMGAINEKSRTPL---APFCIGFTVTVDILA 210

  Fly   198 AGLFTGASMNPTRSLGPAVWNDSWAHHWIYWVGPLVAGAVTSLIYRMAFKGDEEIDL 254
            .|..:||.|||.|:.||||..|.|..|||||||||..|.:...|.|:.. ||::|.|
Frog   211 GGAISGACMNPARAFGPAVVADYWTFHWIYWVGPLAGGLLVGGIIRLCL-GDKKIRL 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	77/215 (36%)
aqp8	NP_001107728.1	MIP	48..258	CDD:294134	79/220 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4373
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.000