DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eglp2 and Eglp3

DIOPT Version :9

Sequence 1:	NP_788433.2	Gene:	Eglp2 / 37737	FlyBaseID:	FBgn0034883	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_611812.2	Gene:	Eglp3 / 37738	FlyBaseID:	FBgn0034884	Length:	270	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	141/279 - (50%)
Similarity:	182/279 - (65%)	Gaps:	18/279 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IGHQMKMSSEEPPSGKQTCRSQSNCWLLQRRQLDSITTVLAEMIATAMLMFLGCMGSVENSVFTN 75
            :..|.:.|.|..|:.:         |.|:..|..:|.....|:.|||:.:|:.|||.||..:|.|
  Fly     1 MSQQKQKSQESNPNAR---------WRLEGHQRSAIACFFGELAATAVFVFIACMGCVETPLFQN 56

  Fly    76 SDFQSALNFGFVVLICIQCFGCVCGAHLNPAVTLATYVYNMISLPMALAYFVAQMVGAFIGYGLL 140
            |.|:|.|.||..:||.|||||.|.|||||||:|||.::|..|....|:||||||..||.||||||
  Fly    57 SHFRSGLTFGLAILIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLL 121

  Fly   141 KAVLPESAIYSAENPNGVCLTSLNSTLTPWQGLAVEFLITCVLISVCCGVWDPRNATKQDSLPVR 205
            .||||.::|...:||:|||:|.|...::..||:.:||||||.|:.|.|.|||||||..|||:|||
  Fly   122 VAVLPGNSIKGVDNPSGVCVTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQDSVPVR 186

  Fly   206 FGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGFWDDHWIYWVGPMAAALITSVIYKHAFRRELE 270
            |||.::||.||||..|||||||.||..||:||..|..||||||||:.|..:||:||:.||:   .
  Fly   187 FGLTVSCLILTAGLFTGASMNPTRSLGPAVWNDSWAHHWIYWVGPLVAGAVTSLIYRMAFK---G 248

  Fly   271 ESEVDETTMSTKRTSEAEL 289
            :.|:|      .|||:|::
  Fly   249 DEEID------LRTSDAKI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp2	NP_788433.2	MIP	41..261	CDD:294134	125/219 (57%)
Eglp3	NP_611812.2	MIP	30..244	CDD:294134	125/213 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471468
Domainoid	1	1.000	121	1.000	Domainoid score	I3512
eggNOG	1	0.900	-	-		E1_COG0580
Homologene	1	1.000	-	-		H136579
Inparanoid	1	1.050	92	1.000	Inparanoid score	I335
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26905
OrthoDB	1	1.010	-	-		D101773at6656
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		otm51414
orthoMCL	1	0.900	-	-		OOG6_100415
Panther	1	1.100	-	-	P	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X153
	13	12.810