Protein Alignment Eglp2 and AQP4

DIOPT Version :9

• Sequence 1: NP_788433.2
• Gene: Eglp2 / 37737
• FlyBaseID: FBgn0034883
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_001304313.1
• Gene: AQP4 / 361
• HGNCID: 637
• Length: 352
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 90/264 - (34%)
• Similarity: 130/264 - (49%)
• Gaps: 25/264 - (9%)

  Fly    24 SGKQTCRSQSNCWLLQRRQLDSIT-----------TVLAEMIATAMLMF-LGCMGSVENSVFTNS 76
            |.:.|.|....|..|..|:...:.           .|.||.:  |||:| |..:||..|...|..
Human     2 SDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFL--AMLIFVLLSLGSTINWGGTEK 64

  Fly    77 DFQ-----SALNFGFVVLICIQCFGCVCGAHLNPAVTLATYVYNMISLPMALAYFVAQMVGAFIG 136
            ...     .:|.||..:...:||||.:.|.|:|||||:|......||:..::.|..||.:||.||
Human    65 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIG 129

  Fly   137 YGLLKAVLPESAIYSAENPNGVCLTSLNSTLTPWQGLAVEFLITCVLISVCCGVWDPRNATKQDS 201
            .|:|..|.|.|.:      .|:.:|.::..||...||.||.:||..|:.......|.:......|
Human   130 AGILYLVTPPSVV------GGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGS 188

  Fly   202 LPVRFGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGFWDDHWIYWVGPMAAALITSVIYKHAFR 266
            :.:..|.::|...|.|...|||||||.|||.||:..|.|::||||||||:..|::...:|::.|.
Human   189 IALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFC 253

  Fly   267 RELE 270
            .::|
Human   254 PDVE 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp2	NP_788433.2	MIP	41..261	CDD:294134	82/236 (35%)
AQP4	NP_001304313.1	MIP	31..248	CDD:278651	81/224 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850