Protein Alignment Eglp2 and AQP3

DIOPT Version :9

• Sequence 1: NP_788433.2
• Gene: Eglp2 / 37737
• FlyBaseID: FBgn0034883
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_004916.1
• Gene: AQP3 / 360
• HGNCID: 636
• Length: 292
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 83/276 - (30%)
• Similarity: 121/276 - (43%)
• Gaps: 50/276 - (18%)

  Fly    33 SNCWLLQRRQLDSITTVLAEMIATAMLMFLGCMGSVENSVF---TNSDFQSA-LNFGFVVLICIQ 93
            |.|..:...:...:...|||.:.|.:|:..|| |||...|.   |:..|.:. |.|||.|.:.|.
Human     9 SRCGEMLHIRYRLLRQALAECLGTLILVMFGC-GSVAQVVLSRGTHGGFLTINLAFGFAVTLGIL 72

  Fly    94 CFGCVCGAHLNPAVTLATYVY---NMISLPMALAYFVAQMVGAFIGYGLLKAVLPESAIYSAEN- 154
            ..|.|.|||||||||.|....   ..|.||:   |.:||.:|||:|.|::..:..::..:.|:|
Human    73 IAGQVSGAHLNPAVTFAMCFLAREPWIKLPI---YTLAQTLGAFLGAGIVFGLYYDAIWHFADNQ 134

  Fly   155 -----PNGVC----------LTSLNSTLTPWQGLAVEFLITCVLISVCCGVWDPRNATKQDSLPV 204
                 |||..          |..:|.....:.|.|  .||.|||..|     ||.|......|..
Human   135 LFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTA--SLIVCVLAIV-----DPYNNPVPRGLEA 192

  Fly   205 -RFGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGF--W-------DDHWIYWVGPMAAALITSV 259
             ..||.:..:..:.|..:|.::||.|.|.|.::...  |       ..|| :|| |:.:.|:.|:
Human   193 FTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHW-WWV-PIVSPLLGSI 255

  Fly   260 ----IYKHAFRRELEE 271
                :|:......||:
Human   256 AGVFVYQLMIGCHLEQ 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp2	NP_788433.2	MIP	41..261	CDD:294134	78/256 (30%)
AQP3	NP_004916.1	MIP	23..264	CDD:238204	79/253 (31%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:Q96PS8	83..85		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:Q96PS8	215..217		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100415
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X153
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.650