Protein Alignment Eglp2 and AQP8

DIOPT Version :10

• Sequence 1: NP_788433.2
• Gene: Eglp2 / 37737
• FlyBaseID: FBgn0034883
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: XP_011544124.1
• Gene: AQP8 / 343
• HGNCID: 642
• Length: 262
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 80/254 - (31%)
• Similarity: 127/254 - (50%)
• Gaps: 12/254 - (4%)

  Fly    12 GHQMKMSSEEPPSGKQTCRSQS--NCWLLQRRQLDSITTVLAEMIATAMLMFLGCMGSVENSVFT 74
            |.|:.|.  ||..|....|..|  ..|.:...: ..:...|.|::.:|:.:|:||:..:||...|
Human     3 GEQIAMC--EPEFGNDKAREPSVGGRWRVSWYE-RFVQPCLVELLGSALFIFIGCLSVIENGTDT 64

  Fly    75 NSDFQSALNFGFVVLICIQCFGCVCGAHLNPAVTLATYVYNMISLPMALAYFVAQMVGAFIGYGL 139
            .. .|.||..|..:.:.|...|.:.|.|.||||:||..:...::|.|.|.|:|:|::|..:|..|
Human    65 GL-LQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAAL 128

  Fly   140 LKAVLPESAIYSAENPNGVCLTSLNSTLTPWQGLAVEFLITCVL-ISVCCGVWDPRNATKQDSLP 203
            .|||.||...:   |.:|....::.........|..|.::|.:| ::||.|..:.:  ||....|
Human   129 AKAVSPEERFW---NASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEK--TKGPLAP 188

  Fly   204 VRFGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGFWDDHWIYWVGPMAAALITSVIYK 262
            ...|.|:....|..|.::|..|||.|:|.||:....|:.|||||:||:.|.|:..::.:
Human   189 FSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLLIR 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp2	NP_788433.2	MIP	41..261	CDD:444743	71/220 (32%)
AQP8	XP_011544124.1	MIP	39..232	CDD:444743	65/198 (33%)