DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp2 and Aqp8

DIOPT Version :9

Sequence 1:	NP_788433.2	Gene:	Eglp2 / 37737	FlyBaseID:	FBgn0034883	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_062031.1	Gene:	Aqp8 / 29172	RGDID:	2146	Length:	263	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	81/259 - (31%)
Similarity:	127/259 - (49%)	Gaps:	24/259 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 MSSEEPP---------SGKQTCRSQS---NCWLLQRRQLDSITTVLAEMIATAMLMFLGCMGSVE 69
            ||.|:.|         .||:|..:.|   ..|..|     .|...:.|::.:|:.:|:||:..:|
  Rat     1 MSGEQTPMCSMDLREIKGKETNMADSYHGMSWYEQ-----YIQPCVVELLGSALFIFIGCLSVIE 60

  Fly    70 NSVFTNSDFQSALNFGFVVLICIQCFGCVCGAHLNPAVTLATYVYNMISLPMALAYFVAQMVGAF 134
            ||..|.. .|.||..|..:.:.|...|.:.|.|.||||:||..:...:...:.:.|:|:|:.|..
  Rat    61 NSPNTGL-LQPALAHGLALGLIIATLGNISGGHFNPAVSLAVTLVGGLKTMLLIPYWVSQLFGGM 124

  Fly   135 IGYGLLKAVLPESAIYSAENPNGVCLTSLNSTLTPWQGLAVEFLITCVLI-SVCCGVWDPRNATK 198
            ||..|.|.|.||...:   |.:|.....:.......:.|.||.::|.:|: :||.|..:.:  |.
  Rat   125 IGAALAKVVSPEERFW---NASGAAFAIVQEQEQVAEALGVEIVMTMLLVLAVCMGAVNEK--TM 184

  Fly   199 QDSLPVRFGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGFWDDHWIYWVGPMAAALITSVIYK 262
            ....|...|.::....|..|.::||.|||.|:|.||:..|:||.|||||:||:.|.|...::.:
  Rat   185 GPLAPFSIGFSVIVDILAGGGISGACMNPARAFGPAVMAGYWDFHWIYWLGPLLAGLFVGLLIR 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp2	NP_788433.2	MIP	41..261	CDD:294134	71/220 (32%)
Aqp8	NP_062031.1	MIP	40..250	CDD:294134	70/215 (33%)
		NPA 1	94..96		1/1 (100%)
		NPA 2	212..214		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334470
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750