DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp2 and aqp-6

DIOPT Version :9

Sequence 1:	NP_788433.2	Gene:	Eglp2 / 37737	FlyBaseID:	FBgn0034883	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001256246.1	Gene:	aqp-6 / 183121	WormBaseID:	WBGene00000174	Length:	291	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	75/239 - (31%)
Similarity:	114/239 - (47%)	Gaps:	36/239 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 AEMIATAMLMFLGCMGSVENSVFTNSD-FQSALNFGFVVLICIQCFGCVCGAHLNPAVTLATYVY 114
            ||.||..:.:::|.|.:.  .||.:.. ..:|...|..:.:....||.|.|||:|||||....:.
Worm    63 AEFIAVLLFVYIGSMQAA--GVFLHDGVLHAAFAHGVAIFVLAATFGGVSGAHINPAVTFGIALV 125

  Fly   115 NMISLPMALAYFVAQMVGAFIGYGLLKAVLPESAIYSAENPNGVCLTSLNSTLT----PWQ-GLA 174
            ..||...|:.|.|:|::|:..|..|::..||    |...|     :.|..:||.    .|| ||.
Worm   126 GRISPIHAVCYVVSQLLGSVFGALLVRISLP----YKMYN-----VISAGATLCGKGYNWQEGLT 181

  Fly   175 VEFLITCVLIS--VCCGVWDPRNATKQDSLPVRFGLAIACLSLTAGQLTGASMNPVRSFAPAIWN 237
            .|.:.|.:|:.  :.|.|    :..|....|:..|.::....|.||.::||||||.|||.|.|..
Worm   182 AEIVTTYILVQTVLLCAV----DTDKNRLAPLAIGFSLIIEILAAGAISGASMNPARSFGPNIMG 242

  Fly   238 G-------------FWDDHWIYWVGPMAAALITSVIYKHAFRRE 268
            .             :|:.||||::||:..|.|.:.:|:..|.|:
Worm   243 QVFLKPEHLDAQYMYWNYHWIYYIGPIIGAFIAAGVYRMFFARD 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp2	NP_788433.2	MIP	41..261	CDD:294134	72/230 (31%)
aqp-6	NP_001256246.1	MIP	60..282	CDD:238204	73/233 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I3512
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		mtm4734
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920