DRSC/TRiP Functional Genomics Resources

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Protein Alignment Eglp2 and Aqp3

DIOPT Version :9

Sequence 1:NP_788433.2 Gene:Eglp2 / 37737 FlyBaseID:FBgn0034883 Length:290 Species:Drosophila melanogaster
Sequence 2:NP_057898.2 Gene:Aqp3 / 11828 MGIID:1333777 Length:292 Species:Mus musculus


Alignment Length:253 Identity:80/253 - (31%)
Similarity:115/253 - (45%) Gaps:38/253 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 LAEMIATAMLMFLGCMGSVENSVF---TNSDFQSA-LNFGFVVLICIQCFGCVCGAHLNPAVTLA 110
            |||.:.|.:|:..|| |||...|.   |:..|.:. |.|||.|.:.|...|.|.|||||||||.|
Mouse    26 LAECLGTLILVMFGC-GSVAQVVLSRGTHGGFLTINLAFGFAVTLGILVAGQVSGAHLNPAVTFA 89

  Fly   111 TYVY---NMISLPMALAYFVAQMVGAFIGYGLLKAVLPESAIYSAEN-------PN---GVCLTS 162
            ....   ..|.||:   |.:||.:|||:|.|::.. |...||::..|       ||   |:..|.
Mouse    90 MCFLAREPWIKLPI---YALAQTLGAFLGAGIVFG-LYYDAIWAFANNELFVSGPNGTAGIFATY 150

  Fly   163 LNSTLTPWQGLAVEFLITCVLISVCCGVWDPRNATKQDSLPV-RFGLAIACLSLTAGQLTGASMN 226
            .:..|....|...:|:.|..||.....:.||.|......|.. ..||.:..:..:.|..:|.::|
Mouse   151 PSGHLDMVNGFFDQFIGTAALIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVN 215

  Fly   227 PVRSFAPAIWNGF--WDD-------HWIYWVGPMAAALITSV----IYKHAFRRELEE 271
            |.|.|.|.::...  |..       || :|| |:.:.|:.|:    :|:......||:
Mouse   216 PARDFGPRLFTALAGWGSEVFTTGRHW-WWV-PIVSPLLGSIAGVFVYQLMIGCHLEQ 271

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Eglp2NP_788433.2 MIP 41..261 CDD:294134 77/241 (32%)
Aqp3NP_057898.2 MIP 23..264 CDD:238204 78/244 (32%)
NPA 1. /evidence=ECO:0000250|UniProtKB:Q96PS8 83..85 1/1 (100%)
NPA 2. /evidence=ECO:0000250|UniProtKB:Q96PS8 215..217 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167830727
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0580
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100415
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X153
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.640

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