DRSC/TRiP Functional Genomics Resources

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Protein Alignment Eglp2 and Aqp2

DIOPT Version :9

Sequence 1:NP_788433.2 Gene:Eglp2 / 37737 FlyBaseID:FBgn0034883 Length:290 Species:Drosophila melanogaster
Sequence 2:NP_033829.3 Gene:Aqp2 / 11827 MGIID:1096865 Length:271 Species:Mus musculus


Alignment Length:266 Identity:81/266 - (30%)
Similarity:125/266 - (46%) Gaps:20/266 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 WLLQRRQLDSITTVLAEMIATAMLMFLGCMGSVENSVFTNSDFQSALNFGFVVLICIQCFGCVCG 100
            |.|  |.:.....||||.:||.:.:|.|...:::.:....|..|.|:.||..:...:|..|.|.|
Mouse     2 WEL--RSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGTLVQALGHVSG 64

  Fly   101 AHLNPAVTLATYVYNMISLPMALAYFVAQMVGAFIGYGLLKAVLPESAIYSAENPNGVCLTSLNS 165
            ||:|||||:|..|...:|...|..|..||::||..|..:|..:.|      .|....:.:.:|::
Mouse    65 AHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITP------VEIRGDLAVNALHN 123

  Fly   166 TLTPWQGLAVEFLITCVLISVCCGVWDPRNATKQDSLPVRFGLAIACLSLTAGQLTGASMNPVRS 230
            ..|..|.:.||..:|..|:.......|.|.:....|..:..|.::....|.....||.||||.||
Mouse   124 NATAGQAVTVELFLTMQLVLCIFASTDERRSDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARS 188

  Fly   231 FAPAIWNGFWDDHWIYWVGPMAAALITSVIYKHAF---RRELE---------ESEVDETTMSTKR 283
            .|||:..|.:||||::|:||:..|:|.|::|.:..   .:.|:         |.:.|......:|
Mouse   189 LAPAVVTGKFDDHWVFWIGPLVGAVIGSLLYNYLLFPSTKSLQERLAVLKGLEPDTDWEEREVRR 253

  Fly   284 TSEAEL 289
            ....||
Mouse   254 RQSVEL 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Eglp2NP_788433.2 MIP 41..261 CDD:294134 72/219 (33%)
Aqp2NP_033829.3 MIP 3..219 CDD:278651 73/223 (33%)
NPA 1. /evidence=ECO:0000250|UniProtKB:P41181 68..70 1/1 (100%)
NPA 2. /evidence=ECO:0000250|UniProtKB:P41181 184..186 1/1 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 251..271 3/9 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167830731
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0580
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1152704at2759
OrthoFinder 1 1.000 - - FOG0000054
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19139
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
76.850

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