DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eglp2 and aqp4

DIOPT Version :9

Sequence 1:	NP_788433.2	Gene:	Eglp2 / 37737	FlyBaseID:	FBgn0034883	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001304775.1	Gene:	aqp4 / 100487371	XenbaseID:	XB-GENE-487854	Length:	345	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	86/246 - (34%)
Similarity:	124/246 - (50%)	Gaps:	22/246 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 AMLMF-LGCMGSVENSVFTNSDFQS-------ALNFGFVVLICIQCFGCVCGAHLNPAVTLATYV 113
            |||:| |..:||..|  ::..|...       ||.||..:...:||||.:.|.|:|||||:|...
Frog    44 AMLIFVLLSLGSTIN--WSPKDNPQPADLVLIALCFGLSIATLVQCFGHISGGHINPAVTVAMVS 106

  Fly   114 YNMISLPMALAYFVAQMVGAFIGYGLLKAVLPESAIYSAENPNGVCLTSLNSTLTPWQGLAVEFL 178
            ...|||..::.|.|||.:||..|.|:|..|.|      ::....:..|.:|:.|:...||.||.:
Frog   107 MRKISLAKSIFYIVAQCLGAIAGAGILYLVTP------SDVAGNLGATMVNTKLSSAHGLLVELI 165

  Fly   179 ITCVLISVCCGVWDPRNATKQDSLPVRFGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGFWDDH 243
            ||..|:...|...||:......|:.:..|.::|...|.|...|||||||.|||.||:....|:.|
Frog   166 ITFQLVFTICASCDPKRKDISGSVALAIGFSVAIGHLFAIPYTGASMNPARSFGPAVIMNKWESH 230

  Fly   244 WIYWVGPMAAALITSVIYKHAF------RRELEESEVDETTMSTKRTSEAE 288
            |:|||||:..|:|...:|::.:      :..|:|.....|..|..:..|.|
Frog   231 WVYWVGPVLGAVIAGALYEYVYCPDPELKNHLKEVLNKATQPSKGKYKEVE 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eglp2	NP_788433.2	MIP	41..261	CDD:294134	79/211 (37%)
aqp4	NP_001304775.1	MIP	31..248	CDD:278651	79/211 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020