Protein Alignment Eglp1 and AQP5

DIOPT Version :10

• Sequence 1: NP_611810.1
• Gene: Eglp1 / 37736
• FlyBaseID: FBgn0034882
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: NP_001642.1
• Gene: AQP5 / 362
• HGNCID: 638
• Length: 265
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 61/216 - (28%)
• Similarity: 97/216 - (44%)
• Gaps: 25/216 - (11%)

  Fly    14 EFSATALLILLGCMGDSTN-QGGESKFLVASVHYGLTVMVVMHVFGFVSGAHSNPCISISCYLMG 77
            ||.||.:.:..| :|.:.. .......|..::.:||.:..:....|.|||.|.||.|:::..:..
Human    17 EFLATLIFVFFG-LGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGN 80

  Fly    78 YIALEVMMMYVVCQMAGAFLGYFLLMQLLPKELVDKSKPGICLVQPMDTLSTY-QVVIIECLLTA 141
            .|:|.....||..|:.||..|..:|..:.|     .:..|...|..::..:|. |.:::|.:||.
Human    81 QISLLRAFFYVAAQLVGAIAGAGILYGVAP-----LNARGNLAVNALNNNTTQGQAMVVELILTF 140

  Fly   142 VLVLGWCSLWDVRNGRFLDSVAIRMGLLVIACSFAGIQLTGASMNPAKTLVPA-----------I 195
            .|.|...:..|.|....:.|.|:.:||.|......||..||.|||||::..||           :
Human   141 QLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWV 205

  Fly   196 FYGSPNSVLMQLTGQILAAIM 216
            |:..|      :.|.:||||:
Human   206 FWVGP------IVGAVLAAIL 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eglp1	NP_611810.1	GlpF	14..197	CDD:440345	54/195 (28%)
AQP5	NP_001642.1	MIP	4..221	CDD:395174	61/216 (28%)
		NPA 1. /evidence=ECO:0000305|PubMed:18768791, ECO:0000305|PubMed:26569106	69..71		1/1 (100%)
		NPA 2. /evidence=ECO:0000305|PubMed:18768791, ECO:0000305|PubMed:26569106	185..187		1/1 (100%)