| Sequence 1: | NP_477133.1 | Gene: | Pi3K59F / 37733 | FlyBaseID: | FBgn0015277 | Length: | 949 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_008835.5 | Gene: | PRKDC / 5591 | HGNCID: | 9413 | Length: | 4128 | Species: | Homo sapiens |
| Alignment Length: | 316 | Identity: | 72/316 - (22%) |
|---|---|---|---|
| Similarity: | 123/316 - (38%) | Gaps: | 88/316 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 611 LVKLVKLVAKEPGNRNKKTEKFQKLLAEQDMFKVNFTNFE-PIPFPLD------PEIYITKIVPM 668
Fly 669 --RTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLILQMITLMDKLLRRENL----DL 727
Fly 728 KLTPYKVLATSSKHGFLQYVDS----------------------------CTVAEVLAREGNIHN 764
Fly 765 F------------------FRKHH---PCD----------NGPYGISAEVMDTYIKSCAGYCVIT 798
Fly 799 YLLGVGDRHLDNLLLT-TNGKLFHIDFGYILGRD----PKPMPPPMKLSKEMVEAM 849 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pi3K59F | NP_477133.1 | C2_PI3K_class_III | 27..186 | CDD:176042 | |
| PI3Ka_III | 284..561 | CDD:238442 | |||
| PI3Kc_III | 601..945 | CDD:270628 | 72/316 (23%) | ||
| PRKDC | NP_008835.5 | HEAT 1 | 288..323 | ||
| HEAT 2 | 1004..1040 | ||||
| Interaction with C1D. /evidence=ECO:0000269|PubMed:9679063 | 1503..1538 | ||||
| Leucine-zipper | 1503..1538 | ||||
| TPR 1 | 1723..1756 | ||||
| NUC194 | 1816..2202 | CDD:400469 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2050..2073 | ||||
| KIP-binding | 2436..3212 | ||||
| FAT | 3023..3470 | CDD:396714 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 3200..3222 | ||||
| PIKKc_DNA-PK | 3719..4015 | CDD:270716 | 54/255 (21%) | ||
| FATC | 4097..4128 | CDD:396715 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5032 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||