Protein Alignment ItgaPS5 and ITGA10

DIOPT Version :9

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_016858111.1
• Gene: ITGA10 / 8515
• HGNCID: 6135
• Length: 1181
• Species: Homo sapiens
• Alignment Length: 1090
• Identity: 254/1090 - (23%)
• Similarity: 410/1090 - (37%)
• Gaps: 275/1090 - (25%)

  Fly    28 VIDAPKHLKTRMIQVRSSYFGYSLVIRPTSIFV----GAPRAQSTL------ESQGSINETGAVY 82
            |:.|.|:|..|  :.|.:....::::..|..|.    |.|.|...|      ||........|:.
Human   242 VVRAAKNLSRR--EGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALK 304

  Fly    83 RCPLASGSCSHY---VLNDKLNKQFQWLGGSMDGGTKDTDKLL------VCAP--RFFVPKNKNY 136
            .|  .:|..:.|   ||...|.:|            :|....|      ...|  |||.
Human   305 AC--EAGRVTRYGIAVLGHYLRRQ------------RDPSSFLREIRTIASDPDERFFF------ 349

  Fly   137 GQMRGICYWVRDTVADTPPLSDV------RTISLIPSQAEEHF-----MLELGLSAHVTDDNSGF 190
                        .|.|...|:|:      |...|..|.||...     |.::|.|.|...|  |.
Human   350 ------------NVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKD--GI 400

  Fly   191 LIGAPGVRSWKGSVLVHRG------EDLAAQGSYAVKMLDSWDWVKNHFTYVGYALSSGYFSSNN 249
            |.|..|...|.||||...|      ..:|.:..:...:       :||..|:||::||.......
Human   401 LFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPAL-------QNHAAYLGYSVSSMLLRGGR 458

  Fly   250 RTSLLYVTTAPSSVLNTGKAYIFDVVGE-IVRKLHVFHGEQLGEYFGYSVVAEDLNGDGLTDV-V 312
            |   |:::.|| ...:.||...|.:..: .||......|||:|.|||..:...|.:.||.||| :
Human   459 R---LFLSGAP-RFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRDGTTDVLL 519

  Fly   313 VSAPLNALGDSYDVGAIYVFI--NKGLFKFEKKIIRLPLSSGARFGSSLSKVGDINHDGYNDLAV 375
            |:||:.....:.:.|.:||::  .:.|...:..:...| ...||||.::..:.|:|.||:.|:||
Human   520 VAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEP-PQDARFGFAMGALPDLNQDGFADVAV 583

  Fly   376 GAPF--AGNGAVFIFLGSEHGLRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAI 438
            |||.  ...||::::.|::.|:|..|:||:.|.|.   |:....||:.:....|:||:...|:|:
Human   584 GAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASM---PHALSYFGRSVDGRLDLDGDDLVDVAV 645

  Fly   439 GAPGAEAVYLYRAYPVVKIHATVRSESRAI--------RPEQETITVTA--CYRLETTSKARQMQ 493
            ||.|  |..|..:.|:|.:..::....:||        |..||.:.:||  |:::.:.:..|...
Human   646 GAQG--AAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDH 708

  Fly   494 QQELTFRMTIDELLQRVSFAPMRTNEVSFQAQAGLSGSCR-------NFSVG------VHY---- 541
            |..:.|..::||.              :..|:|...||.:       ..|||      :|:
Human   709 QFYMRFTASLDEW--------------TAGARAAFDGSGQRLSPRRLRLSVGNVTCEQLHFHVLD 759

  Fly   542 TGGIFTPIDLELHYEL---AKKIPHSHEAFCESCAVVDPLEPKYATGTLSFMTGCAA-HVCVSDL 602
            |.....|:.|.:.:.|   .|..|..:|.   |...:..|.|        |...|.. :.||:||
Human   760 TSDYLRPVALTVTFALDNTTKPGPVLNEG---SPTSIQKLVP--------FSKDCGPDNECVTDL 813

  Fly   603 QLS-SKDVNSS-----FIFGSLEVLSFSYEITNSGEPAYVAQFNVTSSARLPFAKVPGN------ 655
            .|. :.|:..|     .:.|....:..|..:.|..|.||....::..|..|..|.:...
Human   814 VLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIK 878

  Fly   656 ------------CRVRHEVMLCDLNGGRALARGDSESLTIIFDVTQLSGQSLTIEAAVSSAGMDQ 708
                        |.|.|.|.   ..|.:.     :..|...|..:.|..| :.::...||..:::
Human   879 VECAAPSAHARLCSVGHPVF---QTGAKV-----TFLLEFEFSCSSLLSQ-VFVKLTASSDSLER 934

  Fly   709 NP--KDNTMSTTISLREYAEIDASGGPIDGHIALKEYPYSAEVNNSYEFKSH-------GPSIID 764
            |.  :|||..|:..::           .:.|:.     :|:| :..:.::.|       ||....
Human   935 NGTLQDNTAQTSAYIQ-----------YEPHLL-----FSSE-STLHRYEVHPYGTLPVGPGPEF 982

  Fly   765 ELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQATHGSELVPIKLYDQTNTLAKEYPLEDSSRRAN 829
            :.|:.|.....|.|:|       ..||:|.....||.                .|.|..|....|
Human   983 KTTLRVQNLGCYVVSG-------LIISALLPAVAHGG----------------NYFLSLSQVITN 1024

  Fly   830 RKRRELQQDQYAIMPDVNISDILTKENLPANRT--LVLDCLRGNWTICVRSQMRVQLKPEQPIDL 892
            .....:|.......|.|:..::.....|..:.|  .|:.|..|.  :...:::.|.|       |
Human  1025 NASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQ--LAKGTEVSVGL-------L 1080

  Fly   893 RISFKVDLNDFVN--TFDYLVIFTNVEMFKEGDSTSIALKRNLKPNVIFNYSETPLPI------- 948
            |:..    |:|..  .|..|.:.:..|:..|..|.       |:......:||:.|.:
Human  1081 RLVH----NEFFRRAKFKSLTVVSTFELGTEEGSV-------LQLTEASRWSESLLEVVQTRPIL 1134

  Fly   949 ---WYIILSLIAGHLLLGAMTYILYKLRFFKRGKKEELKRLLEEHRSETK 995
               |.:|.|::.|.|||..:.:.|:||.||..      |::.||.:.|.|
Human  1135 ISLWILIGSVLGGLLLLALLVFCLWKLGFFAH------KKIPEEEKREEK 1178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	23/75 (31%)
		Int_alpha	351..403	CDD:214549	21/53 (40%)
		Int_alpha	417..463	CDD:214549	14/45 (31%)
		Integrin_alpha2	451..836	CDD:337057	87/448 (19%)
ITGA10	XP_016858111.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23220
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940