Protein Alignment ItgaPS5 and zmp:0000001082

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001373553.1
• Gene: zmp:0000001082 / 557935
• ZFINID: ZDB-GENE-140106-42
• Length: 1151
• Species: Danio rerio
• Alignment Length: 1024
• Identity: 208/1024 - (20%)
• Similarity: 370/1024 - (36%)
• Gaps: 270/1024 - (26%)

  Fly    92 SHYVLNDKLNKQ--FQWLGGSMDGGTKDTDKL--LVCAPR----FFVPKNKNYGQMRGICYWVRD 148
            :.:|| :|.:||  .:::.|.  ||..:..:|  |...|:    ||:   |:|..:.|
Zfish   262 NEHVL-EKCDKQNILRYIIGV--GGLANLARLTSLASEPKHNNTFFI---KDYKGLEG------- 313

  Fly   149 TVADTPPLSDVRTISLIPSQAEEHFMLELGLSAHVTD-----DNSGF---------LIGAPGVRS 199
                           |:.:..::.:.:|....||..|     ..|||         ::|:.|...
Zfish   314 ---------------LLDNLQKKIYNIEGSTEAHSKDRLKELSQSGFSVINHKDSVIVGSVGSND 363

  Fly   200 WKGSVLVHRGEDLAAQGSYAVKMLDSWDWVKNHFTYVGYALSSGYFSSNNRTSLLYVTTAPSSVL 264
            |:||:.     ::...|| .||..:..|...:..:|:||:...|     .|..:.::.:......
Zfish   364 WRGSLY-----EVTGSGS-GVKETEIRDPFVSKDSYMGYSAVLG-----ARAGVSFLFSGAPRAE 417

  Fly   265 NTGKAYIFDVVGEIVRKLHVFHGEQLGEYFGYSVVAEDLNGDGLTD-VVVSAPLNALGDSYDVGA 328
            :.|...:|.......|......|||:|.|||.|:...|::.||.:| ::|.|||.........|.
Zfish   418 HMGLVTLFIKNDSSWRVSWNISGEQIGSYFGASLSLLDVDSDGDSDFLLVGAPLFHQSQPRAEGK 482

  Fly   329 IYVF-INKGLFKFEKKIIRLPLSSGARFGSSLSKVGDINHDGYNDLAVGAPFA--GNGAVFIFLG 390
            :||: .:.|.|   :|::.:..|:..||.:||:.:.|:|.|..:|:|||||..  |.|.|:|:||
Zfish   483 LYVYTFSDGPF---QKMLNVSGSNIGRFSASLASLKDLNGDSLSDVAVGAPLENDGEGVVYIYLG 544

  Fly   391 SEHGLR----DEPSQRLDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRA 451
            .  |:|    :...||:...|..|   |...||..||...|:..:...|:.|||.|  .:.|.:|
Zfish   545 D--GMRGINLNHAPQRISGRSVLP---GLQQFGVSLSGQMDMSDDNLTDVVIGARG--GMVLLKA 602

  Fly   452 YPVVKIHATVRSESRAIR------PEQETITV---TACYRL--ETTSKARQMQQQELTFRMTIDE 505
            .||:.:...:......|.      |..:.:.|   |:|:.:  :|:|.....::..::..:.:|.
Zfish   603 RPVMSVSVQLSFSPNEINLNYFECPSDKVLNVFNLTSCFTMKEQTSSNGSLDKKLNVSLELNVDV 667

  Fly   506 L--LQRVSFAPMRTNEVSFQAQAGLSGS--CRNFSVGVHYTGG----IFTPIDLELHYELAKKIP 562
            :  :.|..|....::..:.|....|...  ||:|.|   :..|    ..:|:.:.:::.
Zfish   668 MRGINRGFFVQRDSSSKALQQLLLLDSGIFCRSFPV---FMPGCVADTVSPLKIRMNFS------ 723

  Fly   563 HSHEAFCESCAVVDPLEPKYATGTLSFMTGC-AAHVCVSDLQLSSKDVNSSFIFGSLEVLSFSYE 626
             ..|....|.||:|..........:.|...| :.:.||:||:|.....|::.:..:....:....
Zfish   724 -QSEMSGSSVAVLDVYSRTEEYVEVPFQRNCNSNNSCVADLKLDFSFRNNTLVVANQAHFTLLIS 787

  Fly   627 ITNSGEPAYVAQFNVTSSARLPFAKVPGNCRVRHEVMLCDLNGGRALARGDSESLTIIFDVTQLS 691
            :.|.|:.:    ||.:.....|                            |..||:
Zfish   788 LENPGDDS----FNTSIVLHYP----------------------------DGLSLS--------- 811

  Fly   692 GQSLTIEAA--VSSAGMDQNPKDNTMSTTISLREYAEIDASGGPIDGHIALKEYPYSAEVNNSYE 754
             ..||::.:  .||.|...:...|..:.:|:|..|.....:.......::..:|.:|..:.....
Zfish   812 -NFLTVKPSRTRSSCGDRDSGATNRTTCSINLPVYRSGTTTQFQATFRVSKWDYDWSDMMEMMIT 875

  Fly   755 FKSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQATHGSELVPIKLYDQTNTLAKEY 819
            ..|..........|...||:.:.|.                        |.|.|..:.:.....:
Zfish   876 ANSDNNGNTSAAAVRRSVPVQFAVD------------------------VAISLSAEDSVTYLNF 916

  Fly   820 PLEDSSRRANRKRRELQQDQYAIMPDVNISDILTKENLPANRTLVLDCLRGNWTICVRSQMRVQL 884
            .|||...:..|...:::.              |..:.||...:|.|.|
Zfish   917 SLEDRGPKPLRIVYKVEN--------------LGVKGLPVRVSLHLPC----------------- 950

  Fly   885 KPEQPIDL-RISFKVDLN-----------DFVNTFD----YLVIFTNVEMFKEGDSTSIALKR-- 931
             |..|:.| :..|.|..|           |...|.:    :|...:.|:.....|:|..::|.
Zfish   951 -PTTPVRLSKQKFSVQQNSTDVACTSSEDDHCETIECSQFHLDKHSVVQFILTADATFQSVKEYE 1014

  Fly   932 --------------NLKPNVIFN---YSETPL--------------------PIWYIILSLIAGH 959
                          |:...:.:|   |::|..                    |...:|:|:.||.
Zfish  1015 SKFSFQELRKDFSLNISAELNYNRSRYNQTSTGLKDDPHKSQITVKAEFVLPPNRMLIISVGAGG 1079

  Fly   960 --LLLGAMTYILYKLRFFKRGKKEELKRLLEE----HRSETKEPATDCE 1002
              :||..:.::|.|..||||.:.||.....::    ..|....|..|.:
Zfish  1080 GLILLIIIFFLLVKCGFFKRRRPEEFPSQTDDVSALENSPEDSPLMDTD 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	13/38 (34%)
		Int_alpha	351..403	CDD:214549	22/57 (39%)
		Int_alpha	417..463	CDD:214549	14/45 (31%)
		Integrin_alpha2	453..837	CDD:462478	64/405 (16%)
zmp:0000001082	NP_001373553.1	vWFA	145..314	CDD:469594	16/79 (20%)
		Int_alpha	443..491	CDD:214549	16/47 (34%)
		Int_alpha	505..>546	CDD:214549	19/42 (45%)
		Integrin_alpha2	603..951	CDD:462478	70/455 (15%)