Protein Alignment ItgaPS5 and itga6l

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_021336955.3
• Gene: itga6l / 555254
• ZFINID: ZDB-GENE-040914-57
• Length: 1035
• Species: Danio rerio
• Alignment Length: 1155
• Identity: 270/1155 - (23%)
• Similarity: 457/1155 - (39%)
• Gaps: 301/1155 - (26%)

  Fly     4 LLFLIFLALKYQSNAMNFSPLPNRV----IDAPKHLKTRMIQVRSSYFGYSLV----IRPTS--- 57
            |||.:::.            ||.||    :|....::.|  ....|.||:|:.    ::|:.
Zfish     7 LLFTVWII------------LPARVFVFNLDTQNVMRKR--GEADSLFGFSMAMHHQLKPSDQRV 57

  Fly    58 IFVGAPRAQSTLESQGSINETGAVYRCPLAS--GSCSHYVLNDKLN---------KQFQWLGGSM 111
            :.:|||||:: |..|.: |.:|.:|||...:  ..|....::.|..         ::.||||.|:
Zfish    58 LLIGAPRAKA-LPVQNA-NISGGLYRCKFTTQPDDCERIPVDIKARSKDHPGVDYRENQWLGVSV 120

  Fly   112 D----GGTKDTDKLLVCAPRFFVPKNKNYGQMR--GICYWV-RDTVADTPPLSDVRTISLIPSQA 169
            .    ||     |::.||.|:   ::.::...|  |.|:.: :|.|..|.. :|.|:........
Zfish   121 QSQGRGG-----KVVTCAHRY---QDWSFTNQRLLGRCFVLGQDLVLGTDG-ADTRSFCRTRETD 176

  Fly   170 EEHF-MLELGLSAHVTDDNSGFLIGAPGVRSWKGSVLVHRGEDLAAQGSYAVKMLDSWDWVKNH- 232
            :.:| ..:.|||...:.|:...:.||||...|||.|.:...||.:         |:.::....|
Zfish   177 KHNFGYCQQGLSVAFSKDSKYLVYGAPGAYDWKGIVHMEPVEDFS---------LEIYETADEHE 232

  Fly   233 ------FTYVGYALSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDVVGEIV----------RK 281
                  .:::|:||.:| .:...:..|..|..||.|          :..||::          |.
Zfish   233 LNPVDISSFLGFALDTG-MNLMKKGELNVVAGAPRS----------NHSGEVLLLRPEDRTEARN 286

  Fly   282 L---HVFHGEQLGEYFGYSVVAEDLNGDGLTDVVVSAP-LNALGDSYDV-GAIYVFINKG----- 336
            |   |:..|..|...|||.:...|||.||..|:||.|| .::.....|| ||:|::||:.
Zfish   287 LQVEHILRGPGLASSFGYDLTILDLNADGWDDIVVGAPEFSSKNMDDDVGGAVYIYINQAEGQHW 351

  Fly   337 -----LFKFEKKIIRLPLSSGARFGSSLSKVGDINHDGYNDLAVGAP--FAGNGAVFIFLGSEHG 394
                 :..:.||        .:.||.:::.|||:|.|||.|.|..||  .:|.|.|:|:.||..|
Zfish   352 SHFQPVCLYGKK--------DSMFGLAVAHVGDLNQDGYQDFAASAPNEDSGRGRVYIYHGSAAG 408

  Fly   395 LRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSDIDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHA 459
            ...:|: .|||     |.:...:||..|:...|:||||:.:||:|: .::.|.:||..||:.|..
Zfish   409 FHHKPT-ILDA-----GDHSIKLFGYSLAGNMDMDGNGYPELAVGS-FSDTVLIYRTKPVINIEK 466

  Fly   460 T-------VRSESRAIRPEQETITVTACYRLETTSKARQMQQQELTFRMTIDE------LLQRVS 511
            |       :..:::..:.:...||..:|:.. ||.......:..:.:::..|.      |..||.
Zfish   467 TLTLTPNKIDFKAQDCKRKPCIITAQSCFTY-TTEPQTYNPKLRIEYKLEADTVRRERGLPSRVV 530

  Fly   512 FAPMRTNEVSFQAQAGLSGSCRNFSVGVHYTGGI---FTPIDLELHYELAKKIP-HSHEAFCESC 572
            |..........|.:|....||  ....:...|.|   .|.|.:.|...|....| .:.....:..
Zfish   531 FVNSDAANGRQQLKAQRQKSC--VQTKLRLLGEIQDKLTSISISLSVSLPSDNPKQTIRNLPDLE 593

  Fly   573 AVVDPLEPKYATGTLSFM-TGCAA-HVCVSDLQL--------------------------SSKDV 609
            .|::.|:.|.:...:||: :||.: ::|.|:|||                          |..||
Zfish   594 PVLNTLQEKTSKAEVSFLNSGCGSDNICQSNLQLQYSFCTKDQQQDQCDPLAMENGVPVISPGDV 658

  Fly   610 NSSFIFGSLEVLSFSYEITNS-GEPAYVAQFNVTSSARLPFAKV-------------PGNCRVRH 660
            |.     :|||     .:||: |:.|:..|..|.....|....|             |...|.:.
Zfish   659 NI-----ALEV-----TVTNTGGDDAHHTQLYVMFPEVLHLTSVVPKKNSVTQVQCNPNENRTQA 713

  Fly   661 EVMLCDLNGGRALARGDSESLTIIFDVTQLSGQSLTIEAAVSSAGMDQNPKDNTMSTTISLREYA 725
            :   |.|  |..|.|....|..::.:..:||       ..|:||.:....|      |||:::..
Zfish   714 D---CQL--GNPLKRDAEVSFFLMLNTEKLS-------LRVTSANVTLALK------TISIQDVP 760

  Fly   726 EIDAS----------------------GGPIDGHIALKEYPYSAEVNN--SYEF---------KS 757
            .:.|.                      ||.:....|:|.   ..:|.:  .|||         ||
Zfish   761 IVVAEAKIIFELHLNIIGLAKPSQLFFGGEVKDEKAMKA---EDDVGSLVQYEFRIFNIGRPLKS 822

  Fly   758 HGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQAT-HGSELVPIKLYDQTNTLAKEYPL 821
            .|.::::         |.:.....||.:.::     .||.| .|..::.....:..|||.
Zfish   823 FGSAVLN---------IQWPKATKAGKRLLY-----LMQITDRGKNIIHCTPSEAINTLR----- 868

  Fly   822 EDSSRRANRKRRELQQDQYAIMPDVNISDILT-KENLPANRTLVLDCLRGNWTICVRSQMRVQLK 885
              .:..::|.:|||:::. .:....:.||... ..|....:||.          |......|:|:
Zfish   869 --FNMASSRGKRELERES-GLKALASTSDFFPFLGNKRKYKTLT----------CADELSCVELR 920

  Fly   886 -PEQPIDLRISFKVDLNDFVNTF-------DYLVIFTNVEMFKEGDSTSIALKRNLKPNVIFNYS 942
             |.:.:|......:....:.|||       :||.|..|..:...|...:|.::.:.....:..::
Zfish   921 CPLEALDSSAVILLHARLWNNTFLQEYSSLNYLDIILNASLTLNGTQGNIGMQPSDTKVKLTVFA 985

  Fly   943 E------TPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKRG---KKEEL 983
            |      :.:|.|.|:||::...|||..:.|:|:|......|   |::|:
Zfish   986 ERRPALLSRVPWWLILLSVVTALLLLALLFYLLWKFECLTCGACAKQKEV 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	18/39 (46%)
		Int_alpha	351..403	CDD:214549	21/53 (40%)
		Int_alpha	417..463	CDD:214549	18/52 (35%)
		Integrin_alpha2	453..837	CDD:462478	95/476 (20%)
itga6l	XP_021336955.3	None