Protein Alignment ItgaPS5 and itga11a

DIOPT Version :10

• Sequence 1: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001166098.2
• Gene: itga11a / 541475
• ZFINID: ZDB-GENE-050324-1
• Length: 1190
• Species: Danio rerio
• Alignment Length: 1295
• Identity: 281/1295 - (21%)
• Similarity: 456/1295 - (35%)
• Gaps: 442/1295 - (34%)

  Fly     4 LLFLIFLALKYQSNAMNFSPLPNRVIDAPKHLKTRMIQVRSSYFGYSLVIRPTS----IFVGAPR 64
            ||::.:..:....:..|.....:|:|..|          |.:.|||::......    :.||||
Zfish     8 LLWVFWSVMPGLHDCFNIDTRNHRIIKGP----------RQTQFGYTVQQHIAGGQKWLLVGAP- 61

  Fly    65 AQSTLESQGSINETGAVYRCPLA--SG--SCSHYVLNDKLN------------KQFQWLGGSMDG 113
                ||:.|. ::||.||:|||:  ||  |||      |||            |:...||.::..
Zfish    62 ----LETNGQ-HQTGDVYKCPLSRRSGGPSCS------KLNLGKISLTNVSERKERMRLGMTLSS 115

  Fly   114 GTKDTDKLLVCAP---------------------------------------------------- 126
            ..|| :..:.|.|
Zfish   116 NPKD-NSFVACGPLWSYECGSSYYSTGICSRVNASFKFSRTIAPAFQRCETYMDIVIVLDGSNSI 179

  Fly   127 ---------------RFFVPKNK------NYGQ-------------------------MRG---- 141
                           :|:|...:      .||:                         .||
Zfish   180 YPWNEVQDFLINILRKFYVGPGQIQVGVLQYGEKVVSEFQLNDFRSVEDVVKAARKIGQRGGEET 244

  Fly   142 -----------------------------------------------------------ICYWVR 147
                                                                       :.|:.|
Zfish   245 NTALGINVARSEAFKQGGRRGAKKVMIVITDGESHDSADLQQVIEESEKDGITRYAIAVLGYYNR 309

  Fly   148 DTVADTPPLSDVRTISLIPSQAEEHF------------------------------------MLE 176
            ..:.....|::::.|:..|.  ::||                                    |.:
Zfish   310 RGINPEAFLNEIKYIASDPD--DKHFFNVTDEAALKDIVDALGERIFSLEGTSKNGTAFGLQMSQ 372

  Fly   177 LGLSAHVTDDNSGFLIGAPGVRSWKGSVL--VHRGEDLAAQGSYAVKMLDSWDWVKNHFTYVGYA 239
            .|.|.|..:|  |.|:||.|...|.|:||  ..:|:.:..:.||..:..:.   :|||..|:||.
Zfish   373 AGFSTHTVED--GILVGAVGAYDWNGAVLKETRQGKVVPPKSSYEQEFPEE---LKNHGAYLGYT 432

  Fly   240 LSSGYFSSNNRTSLLYVTTAPSSVLNTGKAYIFDV--VGEIVRKLHVFHGEQLGEYFGYSVVAED 302
            ::|   ..:.|:..|||..|| ...:|||..||.:  .||:. .||...|:|:|.|:|..:...|
Zfish   433 VTS---VVSARSGQLYVAGAP-RFNHTGKVIIFTLKNTGELT-ILHSLKGQQIGSYYGSEIAPVD 492

  Fly   303 LNGDGLTD-VVVSAPLNALGDSYDVGAIYVF--INKGLFKFEKKIIRLPLSSGARFGSSLSKVGD 364
            ::.||:|| ::|:||:...| .::.|.:|::  ..:..|..|..:..|.....|||||:|:.|.|
Zfish   493 IDNDGVTDNLLVAAPMFFSG-GWEKGKVYIYRVTEQPRFILEGSLEVLDQGQNARFGSALAPVPD 556

  Fly   365 INHDGYNDLAVGAPFAGN--GAVFIFLGSEHGLRDEPSQRLDAPSREPGPYGAHMFGQGLSRGSD 427
            :|.|.:||:.||||...:  ||::|:....:.:..:..||:.|....|   |...||:.:....|
Zfish   557 LNGDSFNDVVVGAPLEDDHKGAIYIYHSQRNRILRKYKQRIGAVQLGP---GLQYFGRSIHGKMD 618

  Fly   428 IDGNGFNDLAIGAPGAEAVYLYRAYPVVKIHATVRSESRAI--------RPEQETITVTACYRLE 484
            ::|:...|||:|:.|| ||.|: :..|::|::.||.|...|        |..::...::|...|.
Zfish   619 MNGDDLVDLAVGSLGA-AVLLW-SRSVIRINSVVRFEPSKINIFNKDCRRGGKDVTCMSAIVCLN 681

  Fly   485 TTSKARQMQQQELTFRMTIDELLQRVSFAPMRT-NEVSFQAQAGLS-----GSCRNFSVGVHYTG 543
            .||:......||:..|.:  ...:...|.|... ::...|....|:     .:|.:....|..|.
Zfish   682 VTSRTPINPSQEIALRYS--AFFEEKRFNPRAVFDDPDRQQPQNLTLLPGEETCDHIYFHVMETT 744

  Fly   544 GIFTPIDLELHYELAKKIPHSHEAFCESCAVVDPLEPKYATGTLSFMTGCAA--HVCVSDLQL-- 604
            ....||...:..||. .:.|.        .|:|...|......|.|..||..  | ||.||.|
Zfish   745 DYARPIIFTVETELL-DLYHG--------PVLDDSWPTTVKTQLPFWNGCDEDDH-CVPDLLLQA 799

  Fly   605 -------------------------SSKDVNSSFIFGSLEVLSFSYEITNSGEPAYVAQFNVTSS 644
                                     :|.|.:...|.||...:.....:.|.||.||.|:.|:|.:
Zfish   800 HTDLMNRQQFCGQAFRAASLLCQGHTSTDPSERIIEGSRRKMVVDVRLENRGENAYGAKLNITYT 864

  Fly   645 ARLPFAK--VPGN------CR---VRHEVMLCDLNGGRALARGDSESLTIIFDVT-QLSGQSL-- 695
            ..|.|:.  |..|      ||   .|.....|:::  ....|..|:   :||.:. :.|...|
Zfish   865 QNLRFSSLIVKDNSDIHIDCRNENKRKYEKTCNIS--EPFMRAKSQ---VIFRLEFEFSHSELLD 924

  Fly   696 --TIEAAVSSAGMDQNPKDNTMSTTISLREYAEI---------------DASGGPIDGHIALKEY 743
              .|...|:|.|.:....||:.....:|:..|::               |.|....|
Zfish   925 HVRIILEVTSEGEEVILYDNSNEIFYNLKYEADLLFTRDFYPTRYELKPDLSLEKAD-------- 981

  Fly   744 PYSAEVNNSYEFKSHGPSIIDELTVYVDVPIAYTVTGSAGIKSIFNISSLQMQATHGSELVPIKL 808
            .::...|.:::.::.|...|.:|.:|:.:| ..|..|:    .:..|....:....||:.:|
Zfish   982 DFNPPFNFTFQIQNLGYFPIQDLQLYIAIP-EVTKNGN----QLLQIRDFHIDQIGGSQCIP--- 1038

  Fly   809 YDQTNTLAKEYPLEDSSRRANRKRRELQQDQYAIMPDVNISDILT-----KENLPAN-------- 860
             .|....::..| ||.||.:.                :|.|:.|.     ..|||:.
Zfish  1039 -PQHVAHSRASP-EDLSRTSR----------------LNYSNTLAVPVQCTVNLPSYRDVSVKIG 1085

  Fly   861 ---RTLVLDCLRGNWTICVRSQMRVQLKPEQPIDLRISFKVDLNDFVNTFDYLVIFTNVEMFKEG 922
               ||..|..|:.. |:.:.:...|:|.|..|:.|.....|         .::::    |:.||.
Zfish  1086 GSLRTDALHALKFK-TLELVTTASVELNPSSPMFLPEERPV---------RHIIL----EIRKEE 1136

  Fly   923 DSTSIALKRNLKPNVIFNYSETPLPIWYIILSLIAGHLLLGAMTYILYKLRFFKRGKKEE 982
            |..                    :|||.||.|.:.|.|||..:...|:||.||:|.|:.|
Zfish  1137 DYR--------------------VPIWIIIGSTLGGLLLLSLLILALWKLGFFQRQKRRE 1176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ItgaPS5	NP_611808.2	FG-GAP	294..332	CDD:460357	12/38 (32%)
		Int_alpha	351..403	CDD:214549	20/53 (38%)
		Int_alpha	417..463	CDD:214549	16/45 (36%)
		Integrin_alpha2	453..837	CDD:462478	95/457 (21%)
itga11a	NP_001166098.2	None